布洛芬对药物流产疼痛及成功率影响研究

The effect of ibuprofen on pain relief and success rates of medical abortion

目的:探讨布洛芬对药物流产疼痛及成功率的影响。方法:79例接受药物流产的患者随机分为布洛芬组及对照组,在服用米索前列醇片30min后布洛芬组加服布洛芬片,对照组加服维生素C片,对患者服药后30min,1h,3h,6 h进行视觉模拟评分法(VAS)疼痛评分。比较两组患者的疼痛程度、完全流产率及不良反应的发生情况。结果:布洛芬组在药物流产的疼痛程度上明显轻于对照组,结果均具有统计学意义(P<0.05)。其对药物流产的成功率无明显影响,且并不增加药物流产的不良反应。结论:布洛芬能够在不影响药物流产成功率及加重其并发症的同时,减轻患者的疼痛。

Objective：To discuss the effect of ibuprofen on pain relief and success rates of medical abortion. Methods：Seventy-nine cases who underwent medical abortion were randomly divided into ibuprofen group and control group,after 30 minute of received misoprostol orally,the patients of ibuprofen group received ibuprofen orally,and the control group received vitamin C. To evaluate the visual analogue scale（VAS）of patients after 30 min, 1 h, 3 h, 6 h. Comparing the difference of patients with pain degree ,the success rates of abortion,the side effect. Results ：The pa- tients of ibuprofen group was found to be more slighter pain than control group. The results were statistically signifi- cant （P〈0. 05）. Conclusion .. Ibuprofen had a significant beneficial effect on the need for pain relief during the medical bortion. Ibuprofen did not adversely affect the success rates of medical abortion.