广元市366例肾活检病理资料及流行病学特点

Clinical Epidemiology of 366 Renal diseases in Guangyuan based on Pathology data

目的对四川广元市的肾病患者的肾活检病理资料进行总结并用以推测其流行病学的地方特点。方法收集了该院2004年8月一2011年12月期间收治的366例肾病患者，并对其进行了肾活检资料的分析总结，进而探讨了广元市肾脏病患者的病理类型、临床表现及流行病学特点。结果男性43．4％，女性56．6％，不同年龄段的分布显示在30～50岁之间人群的患病率最高。从疾病临床分型来看，肾病综合征最多为175例（47-8％），第2位的是慢性肾小球肾炎为112例（30．6％）。从病因分类来看366例患者中原发性肾小球疾病（PGD）最多为194例（53．O％），随后依次为继发性肾小球。肾炎141例（38．5％），小管间质疾病（TID）13例（3．6％），代谢性疾病（HERD）为11例（3．0％）。结论广元地区原发性肾小球疾病PGD的疾病病例占总数的53．0％，其中40岁以下患者占69．8％；继发性肾小球疾病SGN占38．5％，其中IgA肾病29.8％、紫癜性肾炎（HSPN）2．5％、狼疮肾炎（LN）5．5％，3种占到继发性。肾脏疾病的98．2％。

Objective Sichuan Guangyuan nephropathy renal biopsy data were summarized and used to speculate that the local characteristics of its epidemiology. Methods Court 2004 to 2011 in December, 366 cases of kidney patients, their renal biopsy da- ta analyzed and summarized, and explored the pathological type of Guangyuan City, kidney disease patients, clinical manifestations and epidemiological school characteristics. Results Male 43.4%, 56.6% of women, different age distribution shows the highest prevalence of between 30 to 50 crowd. Nephrotic syndrome from the disease clinical classification, up to 175 cases （47.8%）, sec- ond place is a chronic glomerulonephritis in 112 cases （30.6%）. From 366 cases in patients with primary glomerular diseases （PGD） in the etiology of view up to 194 cases （53.0%）, followed by secondary glomerulonephritis, 141 cases （38.5%）, tubulointer- stitial disease （TIDs） in 13 cases （3.6%）, metabolic diseases （HERD）, 11 cases （3.0%）. Conclusion The cases of the Guangyuan primary glomerular disease, PGD＇s disease accounted for 53.0% of the total number of patients 40 years of age accounted for 69.8%; secondary glomerular diseases SGN （38.5%） in the text, which, lgA nephropathy,29.8%, purpura nephritis （with HSPN） 2.5%, lupus nephritis （LN） 5.5%, three kinds of secondary renal disease accounted for 98.2%.