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脐血源间充质干细胞治疗肌萎缩侧索硬化的临床研究 被引量:2

Clinical study on umbilical cord blood mesenchymal stem cells treatment of amyotrophic lateral sclerosis
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摘要 目的对脐血间充质干细胞(uMSCs)治疗肌萎缩侧索硬化进行研究。方法将脐血间充质干细胞用腰穿的方法移植入肌萎缩侧索硬化患者的脑脊液中,术后给予鼠神经生长因子,比较患者治疗前后的变化。结果采用Norris评分量表,表明患者治疗前后的病情有显著改善,差异具有统计学意义(P<0.05)。结论脐血间充质干细胞对治疗肌萎缩侧索硬化有一定的临床效果。 Objective Study of umbilical cord blood mesenchymal stem cells treatment on amyotrophic lateral sclerosis.Methods Transplant the umbilical cord blood mesenchymal stem cells into amyotrophic lateral sclerosis patients’ cerebrospinal fluid by lumbar puncture, give muse nerve growth factor to those patients, then compare the changes of patient before and after treatment.Results Use Norris score scale, show the patient's condition a significant improvement before and after treatment, with statistically significant differences(P<0.05).Conclusion The treatment of umbilical cord blood mesenchymal stem cells on amyotrophic lateral sclerosis have some clinical effect.
出处 《中外医疗》 2012年第21期68-69,共2页 China & Foreign Medical Treatment
关键词 脐血 间充质干细胞 肌萎缩侧索硬化症 Umbilical cord blood Mesenchymal stem cells Amyotrophic lateral sclerosis
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