抽吸导管在急诊经皮冠状动脉介入术中的临床应用研究

Research of Clinical Application of Aspiration Catheter in Emergency PCI Technique

目的分析在急性心肌梗死行经皮冠状动脉介入术(PCI)的治疗过程中应用血栓抽吸导管的临床疗效。方法选取我院2010年4月至2011年4月收治的120例急性心肌梗死行PCI术治疗的患者,随机分为观察组66例(采用血栓抽吸导管)和对照组54例(传统PCI术),比较两组患者的相关监测指标,并对结果进行统计分析。结果观察组中灌注显影3级和心肌染色3级均高于对照组,比较差异有统计学意义;两组患者左心射血分数、ST段回落率、30 d内心源性死亡、30 d内再梗死以及30 d主要心脏不良事件比较差异均无统计学意义(P>0.05)。结论在急性心肌梗死患者的急诊PCI术中采用抽吸导管能够改善梗死相关血管的前向血流情况,降低无复流和慢血流的发生率,改善心肌再灌注,短期疗效显著。

Objective To analyze the clinical efficacy of thrombus aspiration catheter in pereutaneous coronary intervention（PCI） in the treatment of acute myocardial infarction. Methods 120 cases of acute myocardial infarction patients treated with PCI in our hospital from Apr. 2010 to Apr. 2011 were selected and divided into the observation group（ using a thrombus suction catheter） and control group（ traditional PCI surgery）. Different monitoring indexes of the two groups were compared, and the result of the line statistical analysis. Results in observation group, TIMI3 level and MBG3 level were higher than that in control group, the difference was statistically significant; ejection fraction in patients with ST segment resolution rate, 30 d inner source death,30 d in the terrier and 30 d MACE of observation group showed down trend compared with control group, there were no significant differences between them（ P 〉 0.05 ）. Conclusion Intraopera- tire aspiration catheter in emergency PCI in the patients with acute myocardial infarction can improve the in- farction related artery anterior blood flow, reduce no-reflow and slow flow rate, improve myocardial reperfu- sion, with significant short-term effect.