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水充盈法定位对减少胃癌放疗靶区偏移的研究

Water-filling Method to Reduce Target Volume Shift in Radiotherapy for Gastric Cancer
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摘要 目的探讨水充盈法定位对减少胃癌放疗靶区偏移的影响。方法将10例胃癌患者按随机数字表法分为研究组和对照组,每组5例。研究组放疗定位前及放疗前空腹饮等量水,胃处于水充盈等积扩张下进行定位及放疗;对照组胃充盈度不做饮水要求。2组患者在模拟定位机下观察胃动度,在CT定位扫描后复位观察胃靶区移动度。结果研究组模拟定位机下观察胃动度及在CT定位扫描后复位观察胃靶区移动度均明显低于对照组(P<0.05)。结论水充盈法定位、胃处于等积扩张下进行靶区勾画及放疗,可以减少靶区偏移,保护正常组织并减低毒性。 Objective To evaluate the efficacy of water-filling method in reducing target volume shift in radiotherapy for gastric cancer.Methods Ten patients with gastric cancer were randomly divided into two groups,with 5 patients in each group.The treatment group was given the same amount of water during fasting,followed by CT scan and radiotherapy.The control group were not received drinking water.Gastric motion was observeda using a simulator machine,and target volume shift was determined after CT localization.Results Compared with control group,the degrees of gastric motion and target volume shift significantly decreased in treatment group(P〈0.05).Conclusion Water-filling method can reduce target volume shift,protect normal tissue and alleviate toxicity in radiotherapy for gastric cancer.
作者 张锡泉
出处 《实用临床医学(江西)》 CAS 2012年第7期1-2,5,共3页 Practical Clinical Medicine
关键词 水充盈法 胃癌 放疗 靶区偏移 water-filling method gastric cancer radiotherapy target volume shift
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参考文献7

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