环磷腺苷葡胺治疗毛细支气管炎临床疗效观察

Effects of meglumine adenosine cyclophosphate for treatment of bronchiolitis

目的探讨环磷腺苷葡胺治疗毛细支气管炎临床疗效与安全性。方法对我院儿科收住的120例毛细支气管炎患儿随机分为治疗组与对照组。两组均给予常规治疗,治疗组给予环磷腺苷葡胺注射液,每日2～5 mg/kg,静脉滴注,每日1次。观察两组患儿咳嗽、气促、喘息、肺部体征改善时间及住院天数。结果治疗组有效率(93.3%)明显高于对照组(80%),P<0.05。治疗组咳嗽、气促、喘息、肺部体征改善时间及住院天数较对照组明显缩短,P<0.05。结论环磷腺苷葡胺治疗毛细支气管炎疗效确切,安全可靠,值得临床推广应用。

Objective To explore the effect of meglumine adenosine cyclophosphate on bronchiolitis. Method 120 infants with bronchiolitis were randomly divided into treatment group and control group. Two groups were given conventional treatment, and the treat- ment group plus meglumine adenosine eyelophosphate injection, daily 2 -5 mg/kg, intravenous drip, 1 time a day. The symptoms such as cough, wheezing and shortness of breath, time of improvement in pulmonary sign and hospital days were observed. Result The effective rate of treatment group （93.3%） was significantly higher than that in control group （ 80% ） , and the difference was statistically significant （x2 = 4. 615 ,P 〈 0.05 ）. The symptoms such as cough, wheezing and shortness of breath, time of improvement in pulmonary sign and hospital days in treatment group was significantly shorter than those in the control group （ P 〈 0. 05 ）. Condusion Meglumine adenosine cyclophosphate had a good effect on bronchiolitis, which is safe, reliable and worthy of clinical application.