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美托洛尔联合贝那普利治疗慢性心力衰竭临床观察 被引量:1

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摘要 目的观察美托洛尔联合贝那普利治疗慢性心力衰竭的临床疗效。方法选择慢性心力衰竭患者90例,随机分为治疗组与对照组,每组45例,对照组给予心衰的常规治疗(强心剂、利尿剂、硝酸酯类等扩血管药物),治疗组在常规治疗的基础上加用美托洛尔和贝那普利,12周后观察两组在治疗前后6min内步行距离、左室舒张末内径(LVEDD)、左室收缩末内径(LVESD)和左室射血分数(LVEF)的变化及心功能改善情况,并随访6个月。结果①治疗组总有效率91.11%;对照组总有效率71.11%,两组比较有显著性差异(P<0.05);②12周后治疗组与对照组治疗前后比较6min内步行距离显著提高(P<0.05),LVEDD和LVESD显著减小(P<0.05),LVEF显著提高(P<0.05);③随访半年,对照组死亡3例,治疗组无一例死亡;对照组再住院率为33.33%,治疗组为11.11%。结论美托洛尔与贝那普利联合治疗慢性心力衰竭,患者不仅可以耐受用药,还可显著提高疗效,改善症状及明显提高运动耐量,减少猝死率及再住院率。
作者 黄淑荣
出处 《中国卫生产业》 2012年第23期61-62,共2页 China Health Industry
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