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血脂正常患者颈动脉斑块与血脂、脂蛋白、载脂蛋白关系的研究 被引量:2

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摘要 目的:研究血脂正常患者颈动脉斑块与血脂、脂蛋白、载脂蛋白的关系。方法:选择体检发现颈动脉粥样斑块者作为观察组,同期体检未见颈动脉斑块者作为对照组,并进一步分别根据斑块稳定性和血管狭窄程度将观察组分类,检测血液中甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、载脂蛋白A-Ⅰ(ApoA-Ⅰ)、载脂蛋白B(ApoB)。结果:观察组TC、TG水平与对照组差异无统计学意义(P>0.05),LDL、ApoB水平明显高于对照组,HDL、ApoA-Ⅰ水平明显低于对照组;斑块性质越硬、宫腔越狭窄,LDL、ApoB水平越高,HDL、ApoA-Ⅰ水平越低。结论:脂蛋白、载脂蛋白可以更敏感的反应颈动脉斑块的形成情况,LDL、ApoB水平升高、HDL、ApoA-Ⅰ水平降低与颈动脉斑块的形成密切相关。
出处 《中国医学创新》 CAS 2012年第25期32-33,共2页 Medical Innovation of China
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