阿奇霉素序贯疗法联合布地奈德雾化吸入治疗小儿支原体肺炎的疗效观察

Observation on effect of azithromycin sequential therapy combined with inhalated budesonide in treatment with mycoplasma pneumonia children

目的观察阿奇霉素序贯疗法联合布地奈德雾化吸入治疗小儿支原体肺炎的疗效。方法 2009年5月～2011年4月,50例小儿支原体肺炎患儿随机分为两组,观察组25例采用阿奇霉素序贯疗法联合布地奈德雾化吸入治疗,对照组25例仅采用阿奇霉素序贯疗法治疗,比较观察两组的临床效果和临床症状、体征的变化。结果观察组的总有效率明显高于对照组,(P<0.05)。观察组咳嗽消失、发热消退、气促消失、肺部啰音消失及住院时间均明显短于对照组(P<0.05)。结论阿奇霉素序贯疗法联合布地奈德雾化吸入治疗对支原体肺炎患儿进行治疗,疗效显著,能够明显改善临床症状和体征,缩短治疗时间,值得临床推广应用。

Objective To observe the effect of azithromycin sequential therapy combined with inhalated budesonide in treating mycoplasma pneumonia children.Methods From May,2009 to April,2011,50 cases of mycoplasma pneumonia children were randomly classified into two groups,which observation group with 25 cases was treated with azithromycin sequential therapy combined with inhalated budesonide and control group with 25 cases was treated with azithromycin sequential therapy only.The clinical effect and clinical symptoms and signs change between the two groups were compared.Results The total effective rate in observation group was significantly higher than that in control group（P0.05）.The time of cough disappeared,fever subsided,breath shortness disappeared,pulmonary rales disappeared and stay length in observation group was significantly shorter than those in control group（P0.05）.Conclusions Azithromycin sequential therapy combined with inhalated budesonide in treating mycoplasma pneumonia children can enhance clinical effect rates and improve clinical symptoms and signs,which can be applied in clinic.