女贞子抗炎、抗肿瘤和免疫调节作用的研究进展

Advances in studies on anti-inflammation, antitumor, and immunoregulation of Ligustri Lucidi Fructus

女贞子是一味著名的补益类中药,《神农本草经》记载其具有补中、安五脏、养精神、除百疾等功效。现代医学认为炎症或免疫功能异常是包括肿瘤在内的许多疾病的病理、生理过程。女贞子具有抗非特异性炎症、抗变态反应性炎症、抗肿瘤及免疫调节作用,红景天苷、酪醇、羟基酪醇、齐墩果酸、熊果酸和多糖是其主要活性成分,因此其具有极高的医药保健价值,经深度研究后可开发为抗炎、抗肿瘤新药。

Ligustri Lucidi Fructus is a well-known invigorator in Chinese materia medica with the effects of tonifying middle, calming five zang-organs, cultivating spirit, eliminating all diseases recorded in Shennong Bencao Jing. In modem medicine, inflammation or disorder of immune function is considered to be a common pathophysiologic change in the most diseases including tumor. Ligustri Lucidi Fructus has antinonspecific inflammation, anti-allergic inflammation, antitumor with immunoregulation. Salidroside, tyrosol, hydroxytyrosol, oleanolic acid, ursolic acid, and polysaccharides are the main pharmacologically active components in Ligustri Lucidi Fructus. So it has great value in medical health, and may be developed to a new drug on anti-inflammation and antitumor through further research.