脂肪肝的超声定量诊断及其与血糖血脂体质指数的相关性分析

Quantitative ultrasonic diagnosis of fatty liver and blood lipid and body mass index correlation analysis

目的探讨超声定量诊断（quantification laboratory-region of interest，QLab—ROI）技术无创性测定肝脏超声强度在诊断弥漫性脂肪肝中的临床应用价值；分析脂肪肝轻重程度与血糖、血脂及体质指数之间的关系。方法应用超声定量诊断技术对395例（不同程度）弥漫性脂肪肝患者和142例健康对照者进行肝脏超声强度测量，比较并分析各组之间的差异。结果各组间肝脏超声强度测值存在差异（P〈0．01）；重度脂肪肝组与其他3组间超声强度测值之间均存在统计学意义（P〈0．01）；脂肪肝严重程度与超声强度测值存在正相关（r=0．854，P〈0．01）；脂肪肝严重程度与血脂、血糖、体质指数测值也存在正相关（r=0．831，P〈0．05）。结论超声定量诊断技术作为一种无创性检测肝脏超声强度的方法，有助于量化评价弥漫性脂肪肝病变的程度。

Objetcive To evaluate the clinical value of Quantification Laboratory - Region of Interest （ QLab - ROI） technique for noninvasive determination of liver ultrasound in the diagnosis of diffuse fatty liver; Analyse the relevance between diffuse fatty liver and blood lipid, blood glucose between the groups. Methods 395 patients with diffuse fatty liver were evaluated with QLab - ROI, and the results were compared with 142 healthy subjects. Results The value of ROI was different between groups （ P 〈 0.01 ） ; There were significant statistical differences between severe fatty liver group and other 3 groups （ P 〈 0.01 ） ; there were positive correlation between the severity of fatty liver and the value of ROI （ r =0. 854 ,P 〈0.05） ; blood lipid, blood glucose, body mass index values and the severity of fatty liver were positively related （ r = 0. 831, P 〈 0.05 ）. Conclusion Qlab - ROI is a noninvasive detection method of liver ultrasound intensity, contributing quantitative evaluation of diffuse fatty liver disease severity.