磁共振技术指导超急性脑梗死溶栓的研究进展

Advances of hyperacute cerebral infarct thromboysis directed by MRI

卒中是严重危害人类健康的常见病、多发病,其中缺血性卒中占75%～90%,致残率和死亡率都很高,给患者家庭和社会带来沉重的负担。超早期溶栓是治疗脑梗死最有效的手段,在"时间就是大脑"的理念指导下,选择合适的患者快速应用溶栓剂是治疗的关键。核磁共振技术能够在急性缺血性卒中的超早期提供许多有价值的信息,如急性缺血灶的位置、范围;是否存在缺血半暗带以及缺血半暗带的大小;是否有颅内大动脉的闭塞或严重狭窄,甚至能够估计缺血性卒中的发病时间。核磁共振技术无疑对指导脑梗死治疗(尤其是溶栓治疗)及判断预后有极大的价值。

Stroke is a common disease, and ischemic stroke accounts for 75% to 90%. Due to the high rates of morbidity and mortality, a heavy burden is put on the patient＇ s family and the society. Of the treatment means, the most effective is the hyperacute thrombolytic treatment of cerebral infarction. Under the guidance of the ＂time is brain＂ concept, it is the key to select the appropriate patients for rapid application of thrombolytic agents. MRI techniques can provide a lot of valuable information at hyperacute stage of ischemic stroke, such as the location and range of the acute ischemic lesions, the existence of ischemic penumbra, ischemic penumbra size, presence or absence of the main artery occlusion or severe stenosis, and the estimate of the onset time of ischemic stroke. Undoubtedly, MRI techniques show great value in guiding cerebral infarction treatment, especially forthrombolytic treatment, and judging the prognosis.