摘要
目的观察牛初乳冲剂对小鼠免疫功能的影响。方法 BALB/c小鼠连续灌胃30d后检测碳廓清能力、迟发型变态反应、抗体生成细胞数、血清溶血素水平、巨噬细胞吞噬鸡红细胞能力、NK细胞活性及ConA诱导的脾淋巴细胞转化能力等免疫指标。结果牛初乳冲剂对小鼠的脏/体比值、碳廓清能力及NK细胞活性无明显影响;对迟发型变态反应、抗体生成细胞数、HC50、巨噬细胞吞噬鸡红细胞能力及ConA诱导的小鼠淋巴细胞转化有显著作用。结论牛初乳冲剂能增强小鼠免疫力。
Objective To observe the impact of the bovine colostrum granule on immune function in mice.Methods Given BALB/c mice the bovine colostrum granule intragastrically 30 days,we detected immune indicators,including carbon clearance ability,delayed type hypersensitivity,antibody-producing cell count,serum hemolysin level,macrophage phagocytosis of chicken erythrocytes capacity,NK cell activity and ConAinduced lymphocyte transformationability,etc.Results The bovine colostrum granule had no obvious influence on organ weight / body weight,carbon clearance and NK cell activity in mice.However,it had significant effect on delayed type hypersensitivity,antibody-producing cell count,HC50,macrophage phagocytosis of chicken erythrocytes capacity and ConA-induced lymphocyte transformationability.Conclusion The bovine colostrum granule could enhancing Immunity in mice.
出处
《中国医药指南》
2012年第26期18-19,共2页
Guide of China Medicine
关键词
牛初乳
免疫功能
小鼠
Bovine colostrum
Immune function
Mice
