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不同剂量丙泊酚对儿童麻醉深度和应激反应的影响 被引量:2

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摘要 目的探讨不同剂量的丙泊酚对儿童麻醉深度和应激反应的影响。方法将我院40例进行全麻手术的患儿分为观察组和对照组,观察组采用丙泊酚的剂量为15mg/(kg h),每20min按照15、10、8mg/(kg h)减量,对照组采用丙泊酚的剂量为10mg/(kg h),每20min按照10、8、6mg/(kg h)减量,比较两组患儿在麻醉诱导前(T0)、诱导后插管前(T1)、插管后即刻(T2)、切皮时(T3)、拔管时(T4)的心率(HR)、收缩压(SPB)、舒张压(DPB)的变化。并在注射丙泊酚后每2min记录一次脑电双频指数(BIS)。结果观察组的麻醉深度能够达到手术要求,显著优于对照组(P<0.05)。观察组在诱导时、气管插管时、切皮时、拔气管导管时的HR、SPB、DPB均显著小于对照组(P<0.05)。结论丙泊酚的剂量采用15mg/(kg h),可维持较好的麻醉深度,减轻患儿的应激反应。
作者 沈大川
出处 《中国医药指南》 2012年第26期130-131,共2页 Guide of China Medicine
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