摘要
目的:探索中药在糖尿病治疗中的作用特点,为降血糖新药的筛选提供指导依据。方法:分析单味中药治疗糖尿病及其并发症的相关文献,归纳、总结单味中药发挥疗效的活性部位及其作用特点。结果:中医药治疗糖尿病的作用机制和途径表现为具有多向性、多层面、多靶点的药理特点,有着化学合成药物不可比拟的优势,中药在防治糖尿病及其并发症中具有显著的作用,因而中药及其活性成分在糖尿病和糖尿病并发症的预防和治疗方面,有着西药不可替代的综合优势和广阔的应用前景,值得进一步深入研究。结论:单味中药有降血糖的作用,具有活血化瘀、清热解毒、补益功效中2种功效的中药可能是未来降血糖中药研究的重点。
Objective:To explore the functional characteristics of single Chinese medicine in reducing blood sugar,so as to provide guiding basis for screening new medicines of reducing blood sugar.Methods:Related literatures on the treatment of diabetes and its complications treated by single Chinese medicine were analyzed;active sites of exerting therapeutic effect and functional characteristics of single Chinese medicine were summarized and concluded.Results:The functional mechanism and approach of Chinese medicine presented the pharmacological characteristics of pleiotropy,multi-aspects and multi target spots on the treatment of diabetes,which had the incomparable advantage compared with chemical synthetic drugs;Chinese medicine had notable effect in the prevention and treatment of diabetes and its complications.Chinese medicine and its active ingredients had irreplaceable comprehensive advantages and wide application prospect compared with western medicine in the prevention and treatment of diabetes and its complications,and was worthy of further research.Conclusion:Single Chinese medicine has effect on reducing blood sugar.Chinese medicine which has two of the following functions of activating blood flow and removing blood stasis,clearing heat and detoxicating and tonifying might be the key research focus on Chinese medicine with the function of reducing blood sugar in the future.
出处
《中医学报》
CAS
2012年第10期1314-1318,共5页
Acta Chinese Medicine
基金
河南省科技攻关项目(编号:112102310076)
河南省国际合作项目(编号:104300510011)
郑州市科技领军人才(编号:0910SGYS3527)
河南省高校科技创新团队(编号:2012IRTSTHN011)
关键词
单味中药
丹参
牡丹皮
益母草
活血化瘀
清热解毒
补益
糖尿病
降血糖
single Chinese medicine
saliua przewalskii maxim
paeonia suffruticosa
herba leonuri
activating blood flow and removing blood stasis
clearing heat and detoxicating
tonifying
diabetes
reducing blood sugar