参松养心胶囊对急性心肌梗死患者心率变异性的影响

Influence of Shensong Yangxin Capsule on the Heart Rate Variability of Patients with Acute Myocardial Infarction

目的:探讨参松养心胶囊对急性心肌梗死(AMI)患者心率变异性(HRV)的影响。方法:将106例AMI患者随机分为对照组(50例)和治疗组(58例),对照组给予常规治疗,治疗组在对照组基础上加用参松养心胶囊,每次4粒,每日3次,8周为1个疗程。评价治疗前后心率变异性指标的改变。结果:治疗前后比较,两组患者多项时域指标均明显升高,频域指标LF无明显改变,LF/HF明显降低,HF明显升高,两组治疗后比较差异有统计学意义。结论:参松养心胶囊可以明显提高AMI患者心率变异性,提高心肌梗死患者迷走神经张力,降低交感神经张力,改善自主神经的平衡性。

Objective：To explore the influence of Shensong Yangxin Capsule on the heart rate variability（HRT） of patients with acute myocardial infarction（AMI）.Methods：106 cases of AMI patients were randomly divided into the control group（50 cases） and the treatment group（58 cases）.The control group was treated by conventional therapy;the treatment group was additionally given Shensong Yangxin Capsule based on the control group,4 grains every time,3 times per day.8 weeks were one treatment course for both groups.The change of HRV was evaluated before and after treatment.Results：Comparison before and after treatment showed that a number of time domain indexes in the two groups of patients were dramatically increased,and the frequency domain index LF had no obvious change;LF/HF reduced significantly,and HF obviously rised.Comparison in two groups after treatment showed the difference was statistically significant.Conclusion：Shensong Yangxin Capsule not only can significantly increase heart rate variability the of AMI patients,and rise vagus nerve tension of patients with myocardial infarction,but also reduce the sympathetic nervous tension,and improve the balance of autonomic nerve.