急性脑梗死患者皮质醇升高与血清白蛋白关系的探讨

目的:探讨急性脑梗死患者血清白蛋白与皮质醇含量的关系。方法:选取90例急性脑梗死患者,测定血清白蛋白水平并分为高、中、低3组,分别于卒中发作后36～72小时内上午6:00、10:00和下午6:00、10:00测定患者的血清皮质醇水平并进行统计学分析。结果:3组间血清皮质醇水平差异有显著性(P<0.05)。结论:急性脑梗死患者的皮质醇水平与血清白蛋白水平呈负相关。

Objective：To observe the relation- ship between serum albumin and cortisol in patients with acute cerebral infarction. Meth- ods ：90 patients with first -ever acute cere- bral infarction were divided to three groups by the level of serum albumin which was measured within 36h after stroke onset. Ser- um cortisol was measured between 36 and 72h after stroke onset at 6 a. m,10 a. m,6 p. m. and 10 p. m. Results： There were sig- nificant difference between the group of up- per tertile of serum albumin with the groups of lower and middle tertile（ P 〈 0.01 ）. Con- elusion：Low serum albmnin level in patients with acute cerebral infarction is associated with higher serum cortisol level and predis- poses to hypercortisolemia.