急性脑血管病患者脑微出血病灶的演变

Development of cerebral microbleeds in the acute cerebrovascular diseases

目的探讨急性脑血管病患者脑微出血(CMB)病灶的演变。方法选择47例急性脑血管病合并CMB患者,常规行MRI梯度回波T2加权扫描,1年后复查MRI,统计CMB的好发部位及其病灶数目的变化。结果CMB病灶在基底节、皮质—皮质下、小脑及脑干的发病率分别为66.0%、38.3%、14.9%及12.8%,MRI复查前后病灶数目分别为(10.62±16.04)、(11.94±18.31)个(P<0.01)。结论 CMB是一个逐渐进展的脑血管病,好发于基底节、皮质—皮质下区。

Objective To observe the number change of cerebral microbleeds in the brain and to investigate the de velopment of microhleeds. Methods Forty seven patients with acute cerebrovascular diseases had CMB and were scanned GRE-T2 ＊ WI. The patients were followed up for GRE-T2 ＊ WI scan after one year. The locations of CMB in the brain were observed and the CMB number were compared with the first scan. Results The incidences of CMB in the basal ganglion region, in the cortical subcortical region, in the cerebellum and in the brainstem were 66.0% ± 38.3% , 14, 9% and 12.8%. The number of CMB increased from 10.62 ± 16.04 to 11.94 ± 18.31 with a statistically difference （P 〈 O. 01 ）. Conclusions The incidence of CMB is higher, predominantly in basal ganglion and cortical-subcortical region, whereas lower in the cerebellum and brainstem. CMB is considered as a progressive cerebral microangiopalhy.