摘要
目的通过检测慢性特发性尊麻疹（CIU）患者血清抗甲状腺过氧化酶抗体（TPOAb）、抗甲状腺球蛋白抗体（TGAb）、促甲状腺激素受体抗体（TRAb）这三种主要的甲状腺自身抗体和游离三碘甲状球原氨酸（FT3）、游离甲状腺素（FT4）以及促甲状腺激素（TSH）水平，探讨其与慢性特发性荨麻疹发病的相关性。方法对114例慢性特发性荨麻疹患者和59倒健康对照采用电化学发光发检澍血清甲状腺自身抗体和激素。结果慢性特发性荨麻疹患者血清TPOAb、TGAb、TRAb阳性率分剐为28．2％、18．8％、9．7％皆高于健康对照（P〈0．05），有统计学意义；FT3、FT4和TSH与对熙组比较无统计学差异（P〉0．05）。结论甲状腺自身抗体畀常是慢性特发性荨麻疹发病因素之一，对原因不明的慢性特发性荨麻疹患者进行血清甲状腺自身抗体检测有助于病因明确，指导治疗。
Objective By detection chronic idiopathic urticaria （CIU） in patients with serum anti- thyroid peroxides＇ antibody （TPOAb）, anti - thyroglolmlin antibody （TGAb）, thyroid stimulating hormone receptor antibody （TRAb） of the three major thyroid autoanti- body and free three- triiodothyronine （FT3）, free thyroxin （FT4） and thyroid stimulating hormone （of TSH） level, to explore its correlation with the incidence of chronic idiopathic urticaria. Method On 114 eases of CIU in patients with health and 59 eases with electrogenerated chemiluminescence detection of serum thyroid antibodies and hormones. Result Serum TPOAb in patients with chronic idiopathic urticaria, TGAb, TRAb - positive rates were 28.2%, 18.8%, are higher than the health （P〈 0.05）, There is a statistically siguificant;FT3, FT4 and TSH and the control group compare the non - statistics difference （ P 〉 0.05 ）. Conclusion Abnormal thyroid autoantibody is one of the risk factors for chronic idiopathic urticaria, unexplained chronic idiopathic urticaria in patients with serum thyroid autoantihody contribute to a clear cause and guide treatment.
出处
《医学检验与临床》
2012年第4期8-10,共3页
Medical Laboratory Science and Clinics
