益气活血化痰法对医院获得性肺炎患者炎症细胞因子的影响

Effect of Yiqi Huoxue Huatan Method on Inflammatory Cytokines of Patients with Hospital Acquired Pneumonia

目的:观察益气活血化痰法对医院获得性肺炎患者炎症细胞因子的影响。方法:60例医院获得性肺炎患者随机分为治疗组和对照组各30例。对照组采用常规治疗,治疗组在常规治疗基础上加用静滴参麦注射液50 mL、丹参酮ⅡA磺酸钠注射液30 mg,日1次,并痰热清注射液20 mL,日1次,治疗7 d后测定两组患者治疗前后C反应蛋白(CRP)、肾上腺髓质素(ADM)、降钙素(PCT)的含量。结果:治疗组CRP、ADM、PCT含量明显降低,与治疗前、对照组比较均有显著的统计学差异(P<0.05)。结论:益气活血化痰法配合西医治疗医院获得性肺炎能明显降低患者CRP、ADM、PCT水平,有利于保护脏器功能。

Objective： To observe the effect of Yiqi Huoxue Huatan Method on inflammatory cytokines of patients with hospital acquired pneumonia. Methods： 60 cases of hospital acquired pneumonia patients were randomly divided into treatment group and control group with 30 cases in each group. The control group was treated with routine treatment; in addition to the routine therapy, the treatment group was treated with intravenous drip of Shenmai injection 50 mL, A sulfonic acid natrium injection 30mg once a day, and Tanreqing Injection 20 mL once a day. C reactive protein （CRP）, adrenal medulla hormone （ADM）, calcitonin （PCT） content in two groups 7d after the treatment were measured before and after treatment. Results： ADM CRP, PCT content in the treatment group decreased significantly, compared with those before the treatment and the control group, there were significant difference （P 〈 0.05 ）. Conclusion： Yiqi Huoxue Huatan Method combined with Western medicine for patients with hospital acquired pneumonia can significantly reduce levels of CRP, ADM and PCT, is conducive to the protection of organ function.