阶梯式筛查宫颈癌的临床应用

The clinical application of steps screening for cervical cancer

目的:探讨阶梯式筛查宫颈癌的临床应用价值。方法:对患者采用液基细胞学检查(TCT)、阴道镜检查并活检、病理确诊宫颈病变及宫颈癌。结果:2 600例患者TCT阳性324例,阳性率为12.46%,其中低度鳞状上皮内病变(LSIL)、高度鳞状上皮内病变(HSIL)、宫颈癌(CC)与病检的符合率分别为64.47%、85%、100%。324例TCT阳性及31例TCT阴性但临床可疑患者病理确诊为:CINⅠ、CINⅡ、CINⅢ、CC分别为68、45、32、11例,病理确诊CINⅠ及以上病变156例,阳性率为43.94%。结论:采用TCT-阴道镜检查-病理诊断阶梯式方法筛查宫颈癌,能早期发现宫颈病变及宫颈癌,是有效的宫颈癌筛查方法。

Objective： To evaluate the clinical application and value of steps diagnosis screening for cervical cancer.Methods： The patients were checked with liquid based cytology（TCT）,colposcopy and biopsy,pathological diagnosis of cervical lesions and cervical cancer.Results： The 324 cases of TCT examination was positive in 2 600 cases,positive rate was 12.46%,among them,LSIL,HSIL,CC and disease of the consistent rate was respectively 64.47%,85%,100%.The 324 cases of TCT positive and 31 cases of TCT negative was diagnosed pathologically as CIN I 68 cases,CIN II 45 cases,CIN III 32 cases,CC 11cases,the lesions of pathological diagnosis above CIN I was 156 cases,the positive rate was 43.94%.Conclusion： Using TCT-colposcopy-pathological diagnosis of steps screening for cervical cancer would be more effective in early detection of cervical disease and cervical cancer,it was an effective screening method for cervical cancer.