Study on the Effect of Dental Metal Alloys on the Histamine Liberation of Blood Basophiles in Vitro

Biomaterials for restoration or replacement of diseased tissues may have any origin.The major characteristic for biomaterials is biocompatibility.All biomaterials,used in medicine (dentistry,in particular),interreact with the organism tissues.And the changes occur both in the materials and the organism tissues.It is considered that there are no "inert biomaterials." The number of allergic diseases and complications is constantly growing all over the world,taking an important place in the structure of infectious and noninfectious pathology[1].Pollen,household,epidermal,and food-borne allergens,and haptens are the most frequent sources of sensibilization.

Biomaterials for restoration or replacement of diseased tissues may have any origin. The major characteristic for biomaterials is biocompatibility. All biomaterials, used in medicine （dentistry, in particular）, interreact with the organism tissues.