期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

全基因组关联研究文献特征分析

Characteristics of Genome-wide Association Study Literature
原文传递
导出
摘要 目的分析全基因组关联研究(GWAS)英文文献的数据构成特征。方法对国际最新GWAS研究数据库之一—美国国立人类基因组研究所(National Human Genome Research Institute,NHGRI)数据库进行数据挖掘。结果 2005年开始出现GWAS文献,2005-2010年GWAS英文文献分别为2、8、89、151、229和314篇,预计2011年将超出400篇。结论自2005年开始GWAS英文文献逐年增加,且显示出强劲的发展趋势。 Objective To analyze the data constitution features of genome - wide association studies （GWAS） in English literature. Methods National Human Genome Institute GWAS database, one of the latest international research database of GWAS, was meticulously data mined. Results From the first article of GWAS in 2005, the number of English literature in GWAS in each year was 2 in 2005, 8 in 2006, 89 in 2007, 151 in 2008, 229 in 2009, and 314 in 2010. By the year 2011, it is expected to exceed 400 articles. Conclusion From 2005, thenuber of English literatures in GWAS has increased year by year, it shows strong momentum.
作者 林丁 田明 沈萍
机构地区 重庆市肿瘤研究所
出处 《预防医学情报杂志》 CAS 2012年第9期733-740,共8页 Journal of Preventive Medicine Information
基金 重庆市级医学继教项目:渝卫科教[2011]23-632
关键词 全基因组关联研究 GWAS 文献研究 数据挖掘 genome -wide association study GWAS literature research data mining
分类号 G250 [文化科学—图书馆学]
  • 相关文献

参考文献35

  • 1Klein R J, Zeiss C, Chew EY, et al. Complement Factor H Polymorphism in Age - Related Macular Degeneration [ J ]. Science, 2005,308 (5720) : 385-389.
  • 2韩建文,张学军.全基因组关联研究现状[J].遗传,2011,33(1):25-35. 被引量：28
  • 3权晟,张学军.全基因组关联研究的深度分析策略[J].遗传,2011,33(2):100-108. 被引量：19
  • 4Hindorff LA, Junkins HA, Hall PN, eta/. A Catalog of Published Genome - Wide Association Studies. Available at : www. genome, gov/gwastudies. Accessed [ 2011 - 8 - 12 ].
  • 5Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome - wide associ- ation loci for human diseases and traits. Proc Nail Acad Sci USA. [ May 27,2009. ].
  • 6http ://www. genome, gov/26525384.
  • 7Miller EK, Dumitrescu L, Cupp C, et al. Atopy history and the genomics of wheezing after influenza vaccination in chil- dren 6 5- 59 months of age [ J]. Vaccine, 2011, 29 ( 18 ) :3431-3437.
  • 8Horinouchi M, Yagi M, Imanishi H, et al. Association of genetic polymorphisms with hepatotoxicity in patients withchildhood acute lymphoblastie leukemia or lymphoma [ J ]. Pediatr Hematol Oncol,2010, 27 (5) :344-354.
  • 9Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids [J]. Nature,2010, 466(7307):707-713.
  • 10Lango Allen H, Estrada K, Lettre G, et al. Hundreds of variants clustered in genomic loci and biological pathways af- fect human height [ J ]. Nature,2010, 467 (7317) :832-838.

二级参考文献114

  • 1智联腾,周钢桥,贺福初.人类复杂疾病关联研究中群体分层的检出和校正[J].遗传,2007,29(1):3-7. 被引量：6
  • 2Purcell S,Neale B,Todd-Brown K,Thomas L,Ferreira MA,Bender D,Mailer J,Sklar P,de Bakker PI,Daly MJ,Sham PC.PLINK:a tool set for whole-genome association and population-based linkage analyses.Am J Hum Genet,2007,81(3):559-575.
  • 3Klein RJ,Zeiss C,Chew EY,Tsai JY,Sackler RS,Haynes C,Henning AK,SanGiovanni JP,Mane SM,Mayne ST,Bracken MB,Ferris FL,Ott J,Barnstable C,Hoh J.Complement factor H polymorphism in age-related macular degeneration.Science,2005,308(5720):385-389.
  • 4Hakonarson H,Grant SF,Bradfield JP,Marchand L,Kim CE,Glessner JT,Grabs R,Casalunovo T,Taback SP,Frackelton EC,Lawson ML,Robinson LJ,Skraban R,Lu Y,Chiavacci RM,Stanley CA,Kirsch SE,Rappaport EF,Orange JS,Monos DS,Devoto M,Qu HQ,Polychronakos C.A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.Nature,2007,448(7153):591-594.
  • 5Cauchi S,El Achhab Y,Choquet H,Dina C,Krempler F,Weitgasser R,Nejjari C,Patsch W,Chikri M,Meyre D,Froguel P.TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups:a global meta-analysis.J Mol Med,2007,85(7):777-782.
  • 6Sladek R,Rocheleau G,Rung J,Dina C,Shen L,Serre D,Boutin P,Vincent D,Belisle A,Hadjadj S,Balkau B,Heude B,Charpentier G,Hudson TJ,Montpetit A,Pshez-hetsky AV,Prentki M,Posner BI,Balding DJ,Meyre D,Polychronakos C,Froguel P.A genome-wide association study identifies novel risk loci for type 2 diabetes.Nature,2007,445(7130):881-885.
  • 7Hirschhorn JN,Lettre G.Progress in genome-wide association studies of human height.Harm Res,2009,71(Suppl 2):5-13.
  • 8Benjamin EJ,Dupuis J,Larson MG,Lunetta KL,Booth SL,Govindaraju DR,Kathiresan S,Keaney JF,Jr.,Keyes MJ,Lin JP,Meigs JB,Robins SJ,Rong J,Schnabel R,Vita JA,Wang TJ,Wilson PW,Wolf PA,Vasan RS.Genome-wide association with select biomarker traits in the Framingham Heart Study.BMC Med Genet,2007,8(Suppl 1):S11.
  • 9Scuteri A,Sanna S,Chen WM,Uda M,Albai G,Strait J,Najjar S,Nagaraja R,Orr (u) M,Usala G,Dei M,Lai S,Maschio A,Busonero F,Mulas A,Ehret GB,Fink AA,Weder AB,Cooper RS,Galan P,Chakravarti A,Schless-inger D,Cao A,Lakatta E,Abecasis GR.Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.PLoS Genet,2007,3(7):e115.
  • 10Han J,Kraft P,Nan H,Guo Q,Chen C,Qureshi A,Han-kinson SE,Hu FB,Duffy DL,Zhao ZZ,Martin NG,Montgomery GW,Hayward NK,Thomas G,Hoover RN,Chanock S,Hunter DJ.A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.PLoS Genet,2008,4(5):el000074.

共引文献101

预防医学情报杂志
2012年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部