安徽省1062例慢性荨麻疹过敏原检测结果分析

Allergen detection result analysis of 1062 patients with chronic urticaria in Anhui province

目的了解安徽省慢性荨麻疹患者的食入性与吸入性过敏原情况,为该病的预防和治疗提供依据。方法采用酶联免疫分析法,对1062例慢性荨麻疹患者进行吸入性过敏原和食入性过敏原特异性lgE抗体检测。结果 1062例慢性荨麻疹患者过敏原阳性检出率为48.78%(518例),吸入组过敏原的阳性率明显高于食入组,其中粉螨、尘螨(34.56%)、屋尘(10.73%)为主要过敏原。结论安徽省慢性荨麻疹患者吸入性过敏原的检出率明显高于食入性,过敏原以尘螨、粉螨和屋尘多见,找出致病因素对临床治疗慢性荨麻疹有较好的指导意义。

Objective To investigate Anhui province patients with chronic urticaria in ingestion and inhalation allergen conditions respec tively, in order to provide evidence for prevention and treatment. Methods Enzyme immunoassay method was used to test 1 062 patients with chronic urticaria in allergenspecific lgE antibodies. Results The testing results of I 062 cases showed that the total of the positive reaction rates reached 48.78 % （518 positive cases）. Inhalation allergen positive rate was significantly higher than that of ingestion aller gen group. The positive reaction rates of the mites and the house dust reached 34.56% and 10.37% respectively, which were the first and the second in the allergens tested. Conclusion Both ingestion allergens and inhalation allergens are contributing causes to chronic urticaria. The mites and the house dust were perhaps the ordinary pathogenic allergens for the patients with chronic urticaria in Anhui province. Identifying the causative facto~ is of instructive significance for the clinical treatment of chronic urticaria.