线粒体介导的细胞凋亡的研究进展

Study progress of mitochondria in apoptosis

细胞凋亡是由相关基因调控的程序化细胞死亡过程,线粒体在细胞凋亡中起重要的调控作用。该文对Cyt-c、活性氧、Bcl-2及AIF介导的细胞凋亡机制进行综述。

Apoptosis is a highly regulated form of programmed cell death, which plays a key role in the development and homeostasis of muhicelluar organisms. Mitochondria plays an important role in the regulation of apoptosis cell death. Mechanism of cell apoptosis medi- ated by Cyt-c, oxygen and Bcl-2 and AIF are reviewed in this paper.