原发性腹膜后脂肪肉瘤的生物学行为与术后复发的关系

The relationship between biological behavior of primary retroperitoneal liposarcoma and postoperative recurrence

目的 探讨原发性腹膜后脂肪肉瘤的生物学行为与肿瘤术后复发的相关性.方法 回顾分析37例腹膜后脂肪肉瘤的生物学行为.结果 组织学分型、亚型转化、手术方式、周围组织器官浸润对原发性腹膜后脂肪肉瘤术后复发有影响（P〈0.05）.结论 低度恶性的组织学分型、肿瘤无亚型转化、完整和彻底地切除肿瘤、周围组织脏器无浸润的原发性腹膜后脂肪肉瘤术后复发率低.原发性腹膜后脂肪肉瘤术后发生亚型转化后,肿瘤的分化程度降低,恶性度升高,完整和彻底切除率降低,周围脏器的侵袭力增强.

Objective To analyze the relationship between biological behavior of primary retro- peritoneal liposarcoma （PRPLS） and postoperative recurrence. Methods The biological behaviors of PRPLS in 37 clinical cases were retrospectively analyzed. Results Histological type, subtype transforma-tion,operation method and surrounding tissue invasion had effects on postoperative recurrence in PRPLS （P 〈 0.05）. Conclusion The biological behaviors of low grade, no subtype transformation, complete and thorough resection of the tumor and no surrounding tissue invasion could reduce the postoperative recur-rence of primary retroperitoneal liposarcoma. If the postoperative subtype transformation of PRPLS appears, the degree of tumor differentiation would be reduced, the tumor malignancy degree would be elevated, the rate of complete resection of the tumor would be decreased and the surrounding tissue invasion force would be enhanced.