负压创面引流技术在糖尿病足治疗中的作用

Role of negative pressure wound therapy in healing of diabetic foot

目的 分析应用负压创面引流技术和常规敷料治疗糖尿病足溃疡创面的疗效.方法 回顾性分析2008年5月至2010年5月在我院治疗的35例Wagner 3～5级糖尿病足患者资料.20例接受常规敷料治疗;15例接受负压创面治疗.通过创面愈合时间及截肢率评价疗效.结果 负压创面组平均创面愈合时间为（28.21±4.34）d,常规敷料组为（57.35±5.23）d.常规敷料组18例截肢,截肢率为90.00%,2例（10%）接受常规敷料治疗患者保肢成功,而负压创面组5例截肢,截肢率为33.33%,10例（86.67%）患者保留患肢功能.结论 负压创面治疗技术结合清创及适当的抗炎治疗,可以有效的降低糖尿病足患者的截肢率.

Objective To compare the effectiveness of ulcer healing between negative pressure dressing and conventional moist dressing in the treatment of diabetic foot ulcers. Methods The clinical data of 35 patients with diabetic foot ulcers（ Wagner grade 3 - 5 ） from May 2008 to May 2010 were respec-tively analyzed. Twenty patients （ study group） received negative pressure dressing while other 15 patients （ control group）received conventional dressing. Results were compared for wound healing time and amputa-tion rate. Results The average wound healing time in the study group was（ 28.21 ± 4.34）d while the av-erage time in the control group was（57.35 ± 5.23 ）d. In the control group, 18 patients（90% ）had to re-ceive amputation and only 2 patients（ 10% ）treated with standard dressings had successful limb salvage. In the study group,only 5 patients （33.33%）underwent amputation and 10 patients （66.67%）had a func-tional affected limb. Conclusion The negative pressure dressing technique, debridement and appropriate antibiotic therapy enable a lower rate of amputation effectively.