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CTG方案联合HA和IA方案序贯诱导治疗老年人急性髓系白血病36例 被引量:1

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摘要 目的探讨CTG方案(粒细胞集落刺激因子、吡柔比星、阿糖胞苷)联合HA方案(高三尖杉酯碱、阿糖胞苷)和IA方案(去甲氧柔红霉素、阿糖胞苷)治疗老年急性髓系白血病(AML)的疗效币口安全性。方法对36例老年AML患者用CTG方案联合HA和IA方案序贯诱导治疗。结果36例老年AML患者接受本方案治疗完全缓解12例(33.3%),部分缓解14例(38.7%),未缓解8例(2212%)。结论CTG方案联合HA和IA方案序贯诱导治疗老年人AML安全有效。
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出处 《白血病.淋巴瘤》 CAS 2012年第9期559-560,共2页 Journal of Leukemia & Lymphoma
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  • 1Amadori S, Suciu S, Jehn U, et al. Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in palients 61 years of age and older with acute myeloid leukemia: final results of AML-13, a randomized phase-3 study. Blood, 2005, 106: 27-34.
  • 2Witz F, Sadoun A, Perin MC. et al. A placebo-contrnlled study of recombinant human granulncyte-macrophage colony-stimulating factor administered during and after induction trealment for de novo acute myelogennus leukemia in elderly patients. Grnupe Ouest Est Leuc6mies Aigus My61oblastiques (GOELAM). Blood, 1998, 91: 2722-2730.
  • 3陆化,李建勇,葛峥,张晓艳,钱思轩,张建富,吴雨洁.CAG方案治疗老年急性髓细胞白血病疗效分析[J].实用老年医学,2004,18(5):277-278. 被引量:5
  • 4黄黎,黄河,匡跃敏,蒋志勇.CAG方案治疗老年急性髓细胞白血病疗效观察[J].浙江医学,2007,29(5):508-509. 被引量:3
  • 5孙慧平,刘伟红,李军民,陈秋生,陈瑜,陈颖,沈志祥.IA联合CAG方案序贯诱导缓解治疗原发性初治急性髓系白血病[J].白血病.淋巴瘤,2006,15(6):425-427. 被引量:9
  • 6Yamada K, Shirakawa S, Ohno R, et al. A phase Ⅱ study of (2R)-4- 0-tetrahydrupyranyladriamycin (THP) in hematological malignancies.Invest New Drugs, 1987.5: 299-305.

二级参考文献21

  • 1陆化,李建勇,葛峥,张晓艳,钱思轩,张建富,吴雨洁.CAG方案治疗老年急性髓细胞白血病疗效分析[J].实用老年医学,2004,18(5):277-278. 被引量:5
  • 2Rodrigues CA,Chauffaille ML,Pelloso LA,et al.Acute myeloid leukemia in elderly patients:experience of a single center[J].Braz J Med Biol Res,2003,36(6):703
  • 3Behringer B,Pitako JA,Kunzmann R,et al.Prognosis of older patients with acute myeloid leukemia receiving either induction or noncurative treatment:a single-center retrospective study[J].Ann Hematol,2003,82(7):318
  • 4Hirayama Y,Sakamaki S,Takayangai N,et al.Chemotherapy with ubenimex corresponding to patient age and organ disorder for 18 cases of acute myelogeneous leukemia in elderly patients-effects,complicatons and long-term survival[J].Gan To Kagaku Ryoho,2003,30(8):1113
  • 5全国白血病化学治疗讨论会.急性白血病疗效标准[J].中华血液学杂志,1988,9(3):183-183.
  • 6Francis W,Alain S,Marie-Claire P,et al.A placebo-controlled study of recombinant human granulocyte-macrophage colony-stimulating factor administered during and after induction treatment for de novo acute myelogenous leukemia in elderly patients[J].Blood,1998,91(8):2722-2730.
  • 7Rossi H A,O' Donnell J,Sarcinelli F,et al.Granylocytemacrophage colony-stimulating factor (GM-CSF) priming with successive concomitant low-dose Ara-C for elderly patients with secondary/refractory acute myeloid leukemia or advanced myelodysplastic syndrome[J].Leukemia,2002,16(3):310-315.
  • 8Bai A,Kojima H,Hori M,et al.Priming with G-CSF effectively enhanced low-dose Ara-C-induced in vivo apoptosis in myeloid leukemia cells[J].Exp Hematol,1999,27(2):259-265.
  • 9Ohno R,Tomonaga M,Kobayashi T,et al.Effect of granulocyte colony-stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia[J].N Engl J Med,1990,323(13):871-877.
  • 10Miyauchi J,Kelleher C A,Wang C,et al.Growth factors influence the sensitivity of leukemic stem cells to cytosine arabinoside in culture[J].Blood,1989,73(5):1272-1278.

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