摘要
2-脱氧糖糖苷是指糖苷中糖基单元的2位羟基被氢原子取代的糖苷,广泛存在于天然产物中并具有多样的生物活性.综述了近年来2-脱氧糖苷在化学合成方法方面的进展,包括直接醚化法、直接糖苷化法、临时保护基法及非糖物质合成法等.
2-Deoxy-glycosides are monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom. They exist widely in natural products and show various bioactivity. The recent advances in organic synthesis of 2-deoxy-glycosides are summarized mainly focusing on direct etherification, direct glycosidic bond formation, temporary pro- tecting groups, synthesis from non-sugar and so on.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2012年第10期1812-1826,共15页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.81072525
21002014)
教育部博士点新教师基金(No.20100071120051)
中央高校专项基金(No.10FX061)资助项目~~
关键词
2-脱氧糖苷
寡糖
化学合成方法
2-deoxy-glycosides
oligosaccharides
chemosynthesis methodology
