Sagliker综合征病因的初步研究

Etiologic preliminary study of Sagliker Syndrome

目的初步探讨Sagliker综合征的病因,为进一步深入研究找到研究方向。方法选择Sagliker综合征患者(SS组)8例,单纯继发性甲状旁腺功能亢进患者(单纯SHPT组)26例,比较两组患者在性别、年龄、发病原因及骨代谢相关血液指标等方面的差异。结果 SS组男/女比例为0.6:1、平均年龄为44.38岁,单纯SHPT组平均年龄为51.15岁,男/女比例为1:1;SS组的ALP均值为1184U/L,iPTH均值为2109pg/ml,单纯SHPT组的ALP浓度为491 U/L,iPTH 2371pg/ml。结论性别、年龄等因素可能是Sagliker综合征的危险因素。

Objective Discussion of etiology of Sagliker Syndrome to find the direction of further study. Methods Se- lect of 8 patients of Sagliker Syndrome （ SS group） and 26 patients of simple SHPT （ simple SHPT group） who were diagnosed by the Department of Nephrology and the Center of Dentistry of China-Japan Friendship Hospital. Differ- ences between the two groups on gender, age, the cause of SHPT and several bone metabolic related blood parame- ters were compared. Results For SS group, the male/female ratio is 0.6 ： 1, the average of age is 44.38, and for simple SHPT group, the male/female ratio is 1：1, the average of age is 51.15; for SS group, the average of ALP concentration was 1184 U/L, the average of iPTH concentration was 2109 pg/ml, and for simple SHPT group, the average of ALP concentration was 491 U/L, the average of iPTH concentration was 2371 pg/ml. Conclusion Gen- der, age might be risk factors of Sagliker Syndrome.