基于金基纳米粒子修饰的生物传感器研究进展

Progress on Biosensors Modified by Gold-based Nanoparticles

重点介绍了金铂、金银等合金纳米粒子在修饰过氧化氢生物传感器、免疫生物传感器、葡萄糖生物传感器及DNA生物传感器中的应用。金基合金纳米粒子修饰的生物传感器对降低过电位、促进电子传递、提高检测灵敏度和选择性以及保持生物酶活性具有良好的效果。展望了金基纳米粒子在生物传感器领域应用的发展前景。

The hydrogen peroxide biosensor, inanune biosensor, glucose biosensor and DNA biosensor modified by Au-Pt and Au-Ag alloy nanoparticles are introduced. The biosensor modified by gold-based alloy nanoparticles can reduce the over-potential, facilitate electron transfer and improve the detection sensitivity and selectivity, as well as preserve biological activity. Finally, a simple vision in this field are prospected.