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食管癌患者手术治疗前后血清IL-2、IFN-γ、IL-4和IL-10检测的临床意义 被引量:1

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摘要 近年的研究发现,T辅助细胞根据其分泌细胞因子不同可分为Th1和Th2两个功能性亚群。Th1细胞主要分泌IL-2、IFN-γ、IFN-α、IFN-等因子,引导机体的细胞免疫,若体内该因子不足则易发肿瘤。Th2细胞主要分泌IL-4、IL-5、IL-6、IL-10、IL-13等因子,引导机体的体液免疫,过度的分泌与某些自身免疫性疾病有关。目前,肿瘤的Th1/Th2状态为近年来国内外研究的热门课题之一。本文采用ELISA对31例食管癌患者进行了IL-2、IFN-γ、IL-4和IL-10水平检测,旨在探讨患者的Th1/Th2的平衡状态,为肿瘤的免疫治疗提供依据。
出处 《放射免疫学杂志》 CAS 2012年第5期600-600,共1页 Journal of Radioimmanology
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