期刊文献+

巨细胞病毒感染疾病及其治疗新进展 被引量:1

Cytomegalovirus Infection Diseases and the New Therapies
下载PDF
导出
摘要 巨细胞病毒(cytomegalovirus,CMV)为双链DNA病毒,属疱疹病毒科,具有潜伏-活化的生物学特性。它可感染人、牛、马、猪等多种哺乳动物,其中感染人类的CMV称为人巨细胞病毒(human cytomegalovirus,HCMV),且只有HCMV感染人类。儿童感染率较高,流行病学资料显示,大约有30%~70%美国学龄前儿童感染HCMV[1]。先天性及围产期感染HCMV是出生缺陷的主要病毒病因,主要导致肝脏损伤,严重时可伴肝功能衰竭,
机构地区 湖南省儿童医院
出处 《儿科药学杂志》 CAS 2012年第10期54-57,共4页 Journal of Pediatric Pharmacy
  • 相关文献

参考文献2

二级参考文献112

  • 1[10]Li H(李红),Dong YS,Fang F,et al.The inhibitory effect of garlicin and ganciclovir on CMV-induced apoptosis in vitro.Chinese Journal of Pediatrics (中华儿科杂志),1999,37(4):219-223
  • 2[11] Shu SN (舒赛男),Fang F,Dong YS.An experimental study on the effect of allitridin on inhibiting the expression of hCMV immediate-early antigens in vitro.China Journal of Chinese Materia Medica.(中国中药杂志),2003,28(10):967-970
  • 3[12]Rodems SM,Clark CL,Spector DH,et al.Separate DNA elements containing ATF/CREB and IE86 binding sites differentially regulate the human cytomegalovirus UL 112-113promoter at early and late times in the infection.J Virol,1998,72(4):2697-2707
  • 4[13]Wu J,O' Neill J,Barbosa MS,et al.Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.J Virol,1998,72(1):236-244
  • 5[14]Marchini A,Liu H,Zhu H.Human cytomegalovirus with IE-2(UL122) deleted fails to express early lytic genes.J Virol,2001,75 (4):1870-1878
  • 6[15]Ahn JH,Hayward GS.Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection.Virology,2000,274 (1):39-55
  • 7[16]Gawn JM,Greaves RF.Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression.J Virol,2002,76 (9):4441-4455
  • 8[17]Angulo A,Ghazal P,Messerle M,et al.The major immediateearly gene ie3 of mouse cytomegalovirus is essential for viral growth.J Virol,2000,74 (23):11129 -11136
  • 9[18]Murayama T,Mukaida N,Sadanari H,et al.The immediate early gene 1 product of human cytomegalovirus is sufficient for upregulation of interleukin-8 gene expression.Biochem Biophys Res Commun,2000,279 (1):298 -304
  • 10[19]Nie XC (聂兴草),Fang F,Dong YS,et al.Effects of allitridin on the expression of cell cycle related genes in human cytomegalovirus infected cells.Chinese Journal of Microbiology and Immunology (中华微生物学和免疫学杂志),2003,23(9):742-746

共引文献29

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部