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成牙本质细胞在牙感觉传导中作用的研究进展 被引量：3

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摘要 成牙本质细胞(OD)在牙髓组织中位置特殊,具有独特的细胞形态学特征,处于牙髓组织感受外界对牙齿刺激的最前沿。但目前OD在牙感觉传导中的作用及机制尚不清楚。初步研究发现,OD细胞膜上表达机械/温度敏感的瞬时感受器电位(TRP)、Na+、K+、Ca2+通道,具有初级纤毛等感觉相关细胞器。这些离子通道以及初级纤毛可能共同参与了OD的感觉传导过程,因此本文现将最近相关研究做一综述。
作者 吴声 刘梦娇 阙克华
机构地区 天津医科大学口腔医学院
出处 《中华老年口腔医学杂志》 2012年第2期119-122,共4页 Chinese Journal of Geriatric Dentistry
关键词 成牙本质细胞 感觉传导 离子通道 初级纤毛
分类号 R780.2 [医药卫生—口腔医学]
  • 相关文献

参考文献36

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二级参考文献45

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共引文献4

同被引文献45

  • 1宁放,曹东.不同脱敏剂治疗牙本质过敏症的疗效观察[J].上海交通大学学报（医学版）,2011,31(10):1486-1488. 被引量：3
  • 2陈琰,刘洪臣.牙痛的外周及中枢神经传导通路[J].中华老年口腔医学杂志,2006,4(2):108-111. 被引量：5
  • 3Venkatachalam K, Montell C. TRP Channels[J]. Annual Re- view of Biochemistry, 2007, 76:387-417.
  • 4Bautista DM, Siemens J, Glazer JM, et al. The menthol re- ceptor TRPM8 is the principal detector of environmental cold [J]. Nature, 2007, 448(7150): 204-208.
  • 5E1 Karim IA, Linden GJ, Curtis TM, et al. Human odonto- blasts express functional thermo-sensitive TRP channels: implications for dentin sensitivity [J]. Pain, 2011, 152 (10): 2211-2223.
  • 6Yoshiba K, Yoshiba N, Ejiri S, et al. Odontoblast processes in human dentin revealed by fluorescence labeling and trans- mission electron microscopy[J]. Histochem Cell Biol, 2002, 118(3): 205-212.
  • 7Park C-K, Kim MS, Fang Z, et al. Functional expression of thermo-transient receptor potential channels in dental pri- mary afferent neurons: implication for tooth pain[J]. J Biol Chem 2006, 281(25): 17304-17311.
  • 8Kim HY, Chung G, Jo H J, et al. Characterization of dental nociceptive neurons[J]. Journal of dental research, 2011, 90 (6): 771-776.
  • 9Okumura R, Shima K, Muramatsu T, et al. The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels[J]. Arch Histol Cytol, 2005, 68(4): 251-257.
  • 10Son AR, Yarn YM, Hong JH, et al. Odontoblast TRP channels and thermo/mechanical transmission [J]. J Dent Res, 2009, 88(11): 1014-1019.

引证文献3

二级引证文献3

中华老年口腔医学杂志
2012年 第2期

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