脑瘫患儿头颅MR与病因、智能发育相关性研究

A study of the relation about brain MR、pathogenesis and mentel develpment in patients with cerebral palsy.

对 15 0例脑瘫患儿的头颅MR及智能发育进行了检测 ,结果表明 :MR 14例正常 ,136例异常 ,将MR成像结果与DQ及病因分别进行对比研究 ,发现MR异常者DQ发育明显落后于正常者。DQ异常率由高到低排列次序依次为脑发育畸形、脑室周围白质软化 (PVL)、脑萎缩、脑软化。引起脑瘫的主要病因为围产期脑损伤 (难产、新生儿缺氧缺血性脑病 (HIE)占第一位 ,早产、低体重占第二位 ) ,大脑先天发育畸形。故加强围产期保健 ,积极开展对产前各种有害因素的预防 ,减少畸形儿、未成熟儿及低体重儿的出生是降低脑瘫发病率的关键。

To study the relation of the brain MR、pathogenesis and developmental guotient in patients with cerebral palsy.A brain MR scanning was performed,of which 14 cases had normal findings,while 136 cases had abnormal findings,including atrophy of brain.PVL、encephal omalacia、deformity of brain.The reduction of developmental quotient in the MR abnormal group was higher than normal group.The abnormal rate of the encephal omalacia was the hightest. The common pathogenesis of cerebral palsy was dystocia、asphyxia、preterm、lower birth weight and encephal omalacia.Thus,the keys for reducing incidence of cerebral palsy are intension of perinatal period health service,prevention of prenatal numerous harmaful factors,reduction encephal omalacia pretrem、lower birth weight infant and so on.