期刊文献+

抗乙肝病毒靶点研究新进展 被引量:2

The progress in anti-hepatitis B targets
下载PDF
导出
摘要 慢性乙型肝炎是严重威胁人类的一种慢性感染性疾病,目前,虽然临床上对乙肝的治疗有一定的进展,但临床上存在的因病毒变异而导致的耐药问题,仍无法解决,大大限制了抗病毒药物的使用,对治疗带来一定的困难,因此研究新的抗病毒靶点对今后抗病毒治疗有很大意义。本文着重介绍了最新抗病毒靶点的研究进展。 Chronic hepatitis B (CHB) is a serious chronic infectious danger to humans. Although it has some progress in the treatment of CHB on clinical recently, but it is still a great problem and can not be solved that the virus mutation cause clinical resistance, which greatly limits the use of antiviral drugs and brings some difficulties to the treatment. So the study of new antiviral targets is great significance for future antiviral treatment. This paper describes an overview of the progress in the anti-hepatitis B targets.
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2012年第10期733-736,共4页 Chinese Journal of Antibiotics
关键词 HBV HSC70 APOBEC3G 靶点 HBV HSC70 APOBEC3G Targets
  • 相关文献

参考文献4

二级参考文献50

  • 1TANG Ren Xian, GAO Feng Guang, ZENG Ling Yu, WANG Ying Wei and WANG Yu Long.Detection of HBV DNA and its existence status in liver tissues and peripheral blood lymphocytes from chronic hepatitis B patients[J].World Journal of Gastroenterology,1999,5(4):87-89. 被引量:27
  • 2Wei-GuoHu JunWei Heng-ChuanXia Xin-XiuYang FengLi Guang-DiLi YuanWang Zu-ChuanZhang.Identification of the immunogenic domains in HBsAg preS1 region using overlapping preS1 fragment fusion proteins[J].World Journal of Gastroenterology,2005,11(14):2088-2094. 被引量:7
  • 3Anthony PP. Hepatocellular carcinoma: an overview. Histopathology 2001; 39: 109-118.
  • 4International Working Party. Terminology of nodular hepatocellular lesions. Hepatology 1995; 22: 983-993.
  • 5Hirohashi S, Ishak KG, Kojiro M, Wanless IR, Theise ND, Tsukama H, Blum HE, Deugnier Y, Laurent Puig P, Fischer HP, Sakamoto M. Tumors of the liver and intrahepatic bile ducts. Hepatocellular carcinoma In: Hamilton SR, Aaltonen LA, eds. WHO classification. Tumours of the digestive system. 2nd ed. Lyon: IARC 2000: 167.
  • 6Kojiro M. Pathological evolution of early hepatocellular carcinoma. Oncology 2002; 62(Suppl 1): 43-47.
  • 7Sakamoto M, Hirohashi S, Shimosato Y. Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol 1991; 22: 172-178.
  • 8Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 1988; 22: 631-677.
  • 9Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit Rev Eukaryot Gene Expr 1994; 4: 1-18.
  • 10Garrido C, Gurbuxani S, Ravagnan L, Kroemer G. Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem Biophys Res Commun 2001; 286: 433-442.

共引文献132

同被引文献13

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部