摘要
目的 :研究nm2 3-H1 基因在肾母细胞瘤中的表达及意义。方法 :用免疫组化SP法分析nm2 3-H1 基因表达与肾母细胞瘤多种指标的关系。结果 :nm2 3-H1 基因高度表达与肿瘤临床分期、病理分级及淋巴结转移有关 ,与年龄、性别及病理分型无关。结论 :nm2 3-H1 基因能抑制淋巴结癌转移 ,可作为评价肾母细胞瘤恶性程度、肿瘤进展及预后的指标。
s Objective:The expression of nm23-H 1 genes in nephroblastoma was studied in order to evaluate its clinical significance.Methods:The expression of nm23-H 1 genes was examined by SP immunohistochemisty.The relationship between nm23-H 1 expression and several parameters of nephroblastoma were analyzed.Results: The positive expression of nm23-H 1 genes was associated with the stages,the grades and the lymph node metastasis,but it was correlates with the age and sex of the patients as well as the tumor type.Conclusion: The nm23-H 1 gene in nephroblastoma could inhibit the lymph node metastasis of carcinoma,there for it serve as a parameter to judge the malignancy and progression together with prognosis.
出处
《长治医学院学报》
2000年第1期9-10,共2页
Journal of Changzhi Medical College
关键词
膀胱肿瘤
癌
基因
免疫组化
bladder neoplasn
carcinoma
genes immunohistochemistry
