间充质干细胞作为载体在肿瘤治疗中的应用

Mesenchymal stem cells as carriers in cancer therapy

间充质干细胞（MSC）可以直接作用于肿瘤细胞，抑制其生长，并能特异性迁移到损伤部位和肿瘤组织，传递和表达多种抗肿瘤因子。诸多研究将MSC作为诱导肿瘤细胞凋亡、抑制肿瘤细胞分化、抑制肿瘤血管生成药物的载体，并取得了显著抗肿瘤效果。

Mesenchymal stem cells （MSCs） can directly act on tumor cells to inhibit their growth, and could also migrate to the tissue lesions and tumor tissues to transfer and express many kinds of anti-cancer fac- tors. Numerous researches have applied MSCs as carriers of drugs to induce apoptosis, inhibit differentiation of tumor cells and inhibit tumor angiogenesis, and have got outstanding autitumor results.