特异性转移因子辅助治疗难治性结核的研究(Ⅰ.对难治性肺结核免疫功能影响的初步观察)

The Reserch on the Supplementary Treatment of the Difficult-therapy Pulmonary Tuberculosis by the Special Transfer Factor to M. Tuberculosis——I.Apreliminary observation of the effect on the immunologic function

本文报道用结核特异性转移因子辅助治疗难治性肺结核,观察了其对患者免疫功能的影响。结果表明,用该转移因子治疗组与对照组比较IgG和IgA显著下降(p<0.005和0.002),淋巴细胞转化率和E花环形成率均明显回升(p<0.05和0.02)。初步认为结核特异性转移因子可促进重症结核患者免疫功能的恢复,是一值得深入研究的辅助治疗难治性结核的有效免疫调整剂。

The changes of the immunologic functions of the difficult-therapy pulmonary tuberculosis pa- tient treated by the special Transfer Factor to M.tuberculosis were observed in this study.The results indicated that the levels of IgG and IgA in the sera from the patients treated with the special Transfer Factor to M.tuberculosis were significantly lower than those of control group(p<0.001),and that the rates of lymphocyte transtformation and E-rosette formation were significantly higher than those of control group(p<0.001),This TF has the effect of the promating the recovery of the immunologic function of the patient with the difficult-therapy pulmonary tuberculosis.We deem that the TF is one of effect immunoregulatory factor treating the difficult-therapy tuberculosis.