仙璐贝联合鼻渊舒治疗儿童慢性鼻窦炎临床疗效观察

Clinical efficacy observation of sinupret drops combined with Biyuanshu in treatment of children with chronic sinusitis

目的探讨仙璐贝与鼻渊舒口服液治疗儿童慢性鼻窦炎的临床疗效和安全性。方法选取2009年1月～2012年1月在本院儿科住院治疗的108例慢性鼻窦炎患儿为研究对象,运用随机数字表法将本研究入选患者分为对照组和实验组,对照组患儿给予抗生素和仙璐贝治疗,实验组则加用鼻渊舒口服液治疗,比较两组患儿临床疗效和不良反应发生情况。结果实验组患儿治疗的总有效率(94.44%)明显高于对照组(79.63%),对照组和实验组患儿治疗总有效率差异有统计学意义(P<0.05),对照组和实验组患儿不良反应发生率差异无统计学意义(P>0.05)。结论儿童慢性鼻窦炎在抗生素和仙璐贝治疗的基础上加用鼻渊舒口服液临床疗效确切,不良反应少,值得推广。

Objective To investigate the clinical efficacy and safety of sinupret drops and biyuanshu in treatment of children with chronic sinusitis. Methods The clinical data of one hundred and eight cases of children with chronic sinusitis were collected who were treated in the department of paediatrics in our hospital from January 2009 to January 2012, then were divided into control group and observation group by using a random number table, children with chronic sinusitis in the control group were given antibiotics and sinupret drops four weeks, children with chronic sinusitis in the observation group were given Biyuanshu based on control group, its clinical efficacy after 4 weeks were evaluated. Results The total efficient rate was higher in the observation group than that in the control group （94.44% vs 79.63%, P 0.05）, and there was no statistical significance （P 0.05） in adverse reaction rate. Conclusion Sinupret drops and Biyuanshu can obtain satisfactory curative effect in children with chronic sinusitis, it is safe and reliable, it is worthy of applying for clinic.