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胞磷胆碱钠片治疗急性脑出血的临床疗效 被引量:3

The clinical curative effect of citicoline sodium tablets in the treatment of acute cerebral hemorrhage
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摘要 目的探讨胞磷胆碱钠片治疗急性脑出血的临床疗效及安全性。方法将本院住院治疗的急性脑出血患者178例,随机分成治疗组与对照组各89例。对照组患者采用常规的脑出血治疗,治疗组在对照组治疗基础上给予患者胞磷胆碱钠片治疗。结果治疗组与对照组治疗后,神经功能缺损评分均较治疗前有明显改善,但治疗组改善的程度明显大于对照组(P<0.05)。治疗组89例患者的总有效率为95.51%,对照组89例患者的总有效率为69.66%,两组患者总有效率相比,治疗组明显高于对照组,差异有统计学意义(P<0.05)。结论胞磷胆碱钠片治疗急性脑出血是安全的、有效的,可以有效地改善患者的神经功能,值得在临床广泛推广。 Objective To discuss the clinical curative effect and safety of citicoline sodium tablets in the treatment of acute cerebral hemorrhage. Methods One hundred and seventy-eight cases of patients with acute cerebral hemorrhage hospitalized in our hospital were randomly divided into treatment group and control group (n = 89). Patients in control group were given conventional treatment for cerebral hemorrhage. Patients in treatment group were given citicoline sodium tablets on the base of the control group. Results After treatment, the neural function defect scale of the treatment group and control group were obviously improved than before treatment, while the degree of improvement in the treatment group was significantly higher than that in the control group (P 0.05). The total effective rate of 89 patients of the treatment group was 95.51%, the total effective rate of 89 patients of the control group was 69.66%, the total effective rate of two groups was compared, and the treatment group was significantly higher than the control group, the difference was statistically significant (P 0.05). Conclusion The treatment of citicoline sodium tablets in the treatment of acute cerebral hemorrhage is safe, effective, and can effectively improve patients with neural function, it is worthy of clinical promotion widely.
出处 《中国当代医药》 2012年第27期60-61,共2页 China Modern Medicine
关键词 急性脑出血 胞磷胆碱钠片 临床疗效 安全性 Acute cerebral hemorrhage Citicoline sodium tablets Clinical curative effect Safety
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  • 1侯荣华.胞磷胆碱的临床应用[J].医药导报,2003,22(S1):67-68. 被引量:8
  • 2甘晓玲.弱视的定义、分类及疗效评价标准[J].中国斜视与小儿眼科杂志,1996,4(3):97-97. 被引量:1014
  • 3王祖兰,赵逵,魏伟,李成建,柯银花,蒋欣.胞磷胆碱的不良反应[J].天津药学,1995,7(2):31-33. 被引量:3
  • 4李光勤 董为伟.大鼠脑出血周围区白细胞浸润及强力霉素效果的研究[J].中华神经科杂志,1999,32(1):58-59.
  • 5谭安雄,李小云.盐酸多奈哌齐治疗血管性痴呆的疗效观察[J].中原医刊,2007,34(13):78-79. 被引量:5
  • 6史玉泉.实用神经病学[M].第3版.上海:上海科学技术出版社.2005:236.
  • 7王家桥,刘其强,史小红.实用周围神经病学[M].郑州:郑州大学出版社,2001:273-276.
  • 8Zweifler RM. Menbrane stabilizer: citicoline[J]. Curr Med Res Opin,2002,28(2) :14-17.
  • 9Matyja E, Taraszewska A, Nagaflska E, et al. CDP-choline protects motor neurons against apoptotic changes in a model of chronic glutamate excitotoxicity in vitro[J]. Folia Neuropathol,2008, 46(2) :139-48.
  • 10Ozay R, BekarA, KocaeliH, etal. Citicoline improves functional recovery, promotes nerve regeneration, and reduces postoperative scarring after peripheral nerve surgery in rats[J]. Surg Neurol. 2007,68(6):615-22.

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