上海与内蒙古自治区两地自然人群踝臂指数的调查研究

A survey of ankle-brachiai index among natural population in Shanghai and Inner Mongolia Autonomous Region

目的调查上海、内蒙古自治区（简称内蒙古）两地自然人群踝臂指数（ABI），观察下肢外周动脉疾病（PAD）患病率。方法采用分层整群随机抽样的方法，收集上海、内蒙古两地自然人群2604例，最终研究对象为2569例，测量其ABI并收集资料。结果上海、内蒙古两地人群ABI均值分别是1．074±0．095和1．062±0．075（P〈0．001），下肢PAD患病率分别是4．2％和1．9％（P〈0．01）。两地男性ABI均值分别是1．078±0．105和1．075±0．080（P〉0．05），女性ABI均值分别是1．073±0．089和1．052±0．070（P〈0．001），筛查出两地自然人群男性下肢PAD患病人数分别是21例（4．7％）和11例（2．0％）（P〈0．05），两地女性下肢PAD患病分别是36例（4．0％）和12例（1．8％）（P〈0．05）。〈50岁组两地ABI均值分别是1．037±0．082和1．055±0．068（P〈0．05），两地下肢PAD患病分别是8例（7．6％）和9例（1．2％）（P〈0．001）。结论上海自然人群ABI均值高于内蒙古，其下肢PAD患病率无论男女均明显高于内蒙古。不同年龄组两地自然人群下肢PAD患病率的差异仅显示在〈50岁组，上海社区自然人群暴露的动脉粥样硬化性疾病的危险因素可能在增加，需更加关注下肢PAD。

Objective To investigate epidemiological characteristics and differences in ankle- brachial index （ABI） among the natural population in Shanghai and Inner Mongolia, and to observe the prevalence of lower extremity peripheral arterial disease （PAD）. Methods A total of 2604 volunteers from Shanghai and Inner Mongolia were selected by stratified cluster random sample. ABI was measured and related data were collected. Results The ABI value in Shanghai was 1. 074 ＋ 0. 095, while it was 1. 062 ± 0. 075 in Inner Mongolia （ P 〈 0. 001 ）. The prevalence of lower extremity PAD in Shanghai was 4. 2%, while it was 1.9% in Inner Mongolia （P 〈 0. 01 ）. For males, the ABI value in Shanghai was 1. 078 ＋ 0. 105, and it was 1. 075 ~0. 080 in Inner Mongoiia（P 〉0. 05）. For females, the ABI value in Shanghai was 1. 073 ~ 0. 089, while it was 1. 052 ~ 0. 070 in Inner Mongolia （P 〈 0. 001 ）. For males, the prevalence of lower extremity PAD of the in Shanghai was 4. 7% , while it was 2. 0% in Inner Mongolia （ P 〈 0.05 ）. For females, the prevalence of lower extremity PAD of in Shanghai was 4. 0% , while it was 1.8% in Inner Mongolia （P 〈 0. 05 ）. The ABI values in age group of 〈 50 years in Shanghai and Inner Mongolia were 1. 037 ± 0. 082 and 1. 055±0. 068, respectively （ P 〈 0. 05 ）. The prevalences of lower extremity PAD in age group of 〈50 years in Shanghai and Inner Mongolia were 7. 6% and 1.2% , respectively （P 〈0. 001 ）. There were no significant differences in ABI value and the prevalence of lower extremity PAD between Shanghai and Inner Mongolia in both age group of 50-69 years and i〉 70 years （ all P values 〉 0.05 ）. Conclusions The ABI value in Shanghai is higher than that in Inner Mongolia and the prevalence of lower extremity PAD in both males and females in Shanghai is significantly higher than that in Inner Mongolia. But they are lower than the level of western countries. In different age groups, the difference of the prevalence of lower extremity PAD between Shanghai and Inner Mongolia is only displayed in the age group of 〈 50 years,which may be related to the limited sample size. The natural population in Shanghai exposed artery atherosclerotic disease risk factors may increase and we need to pay more attention to the lower extremity PAD.