期刊文献+

头颅局部亚低温联合依达拉奉注射液治疗脑出血的临床疗效与安全性 被引量:5

Head of Local Mild Hypothermia Combined with Edaravone Injection in Treatment of Cerebral Hemorrhage the Clinical Efficacy and Safety
下载PDF
导出
摘要 目的本文主要是探讨研究局部的头颅亚低温联合依达拉奉注射液对于治疗脑出血的临床疗效以及该治疗方案的临床安全性。方法选取我院从2010年3月至2011年3月收治的脑出血患者共65例。随机将患者分为两组,对照组采用常规的非手术保守治疗,观察组在对照组常规治疗的基础上,给予依达拉奉的注射治疗,同时采用半导体的冷冰帽进行局部的头颅亚低温治疗。结果观察组患者的治疗总有效率为83.3%明显高于对照组的77.1%,两组有显著性差异(P<0.01)。两组患者在治疗过程中没有出现有严重的不良反应。结论小头颅局部亚低温联合依达拉奉治疗脑出血能取得满意的治疗效果,且安全性较高,值得临床推广使用。 Objective To analysis the clinical effects of cerebral hemorrhage patients in the treatment of application edaravone combined with local skull mild hypothermia. Methods 65 cases of cerebral hemorrhage patients for the study were randomly divided into two groups, control group given routine treatment. Based on this observation group given edaravone treatment combined with local skull mild hypothermia treatment, comparative analysis of two groups of patients with general information, treatment and clinical efficacy. Results Control group clinical effects rate is 77.1%, and observation group is 83.3% and so the differences were statistically significant. Conclusion Edaravone combined with local skull mild hypotherrnia in the cerebral hemorrhage with a significant effect, can effectively improve the recovery rate of patients, is worthy of clinical use.
作者 彭小莲
出处 《中国医药指南》 2012年第27期31-32,共2页 Guide of China Medicine
关键词 头颅局部亚低温 依达拉奉 脑出血 Edaravone Anisodamine Pediatric critical care rescue
  • 相关文献

参考文献3

二级参考文献9

共引文献65

同被引文献47

  • 1俞磊,况建国,夏亮.4018例颅脑创伤住院患者流行病学特征分析[J].江西医学院学报,2009,49(5):120-122. 被引量:5
  • 2张璇,吴苏宁,张林亭.疏血通注射液对局灶脑缺血自由基损伤的脑保护作用[J].实用心脑肺血管病杂志,2007,15(2):94-95. 被引量:15
  • 3全国第4届脑血管病学术会议.各类脑血管病诊断要点[J].中华神经科杂志.1996.29.
  • 4石磊,夏玲洋,戴晓莉,等.依达拉奉联合亚低温治疗急性重型颅脑损伤疗效观察[J].中国药物经济学,2014,5(8):223-224.
  • 5Jin HY,Lee KA,Wuj Z,et al .The neuroprotective benefit frompioglitazone (PIO)addition on the alpha lipoic acid (ALA)based treatment in experimental diabetic rats [J]. Endocrine,2014,47(3):772-782.
  • 6Idris Z,Zenian MS,Muzaimi M,et al .Better Glasgow outcomescore,cerebral perfusion pressure and focal brain oxygenation inseverely traumatized brain following direct regional brain hypothermiatherapy:a prospective randomized study [J]. Asian JNeurosurg,2014,9(3):115-123.
  • 7Alexandre H,Marcelo F,Rodrigo D,et al .Role of hormonal levelson hospital mortality for male patients with severe traumaticbrain injury[J].Brain Inj,2014,28(10):1262-1269 .
  • 8üsküdarTeke H,Gündüz E,Akay OM,et al . Are the high seruminterleukin 6 and vascular endothelial growth factor levelsuseful prognostic markers in aggressive non hodgkin lymphomapatients[J].Turk J Haematol,2015,32(1):21-28.
  • 9Yaoita T,Sasaki Y,Yokozawa J,et al . Treatment with AntiInterleukin 6 Receptor Antibody Ameliorates Intestinal Polyposisin Apc(Min/+)Mice under High Fat Diet Conditions[J].Tohoku J Exp Med,2015,235(2):127 134.
  • 10Scanzano A,Schembri L,Rasini E,et al .Adrenergic modulationof migration,CD11b {JP3and CD18 expression,ROS and interleukin8 production by human polymorphonuclearleukocytes[J]. Inflamm Res,2015,64(2):127-135.

引证文献5

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部