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腺相关病毒介导血小板源性生长因子基因转染间充质干细胞的研究 被引量:1

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摘要 骨髓间充质干细胞(MSCs)是一类重要的干细胞,在适宜的刺激条件下可分化成为成骨细胞、成心肌细胞及神经细胞等细胞类型,因而被认为是组织工程、细胞及基因治疗理想的靶细胞。血小板源性生长因子-B(PDGF-B)是一种具有促进血管新生及抗凋亡等功能的活性因子。我们通过9型腺相关病毒携带PDGF—B基因,对MSCs进行基因修饰,探讨该基因修饰的可行性、稳定性及安全性。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第10期2094-2094,共1页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助项目(81000089) 新疆维吾尔自治区科技厅青年基金资助项目(2009211820) 新疆维吾尔自治区教育部科学技术研究重点项目(209137)
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