肾母细胞瘤临床病理学特点及预后相关影响因素
摘要
肾母细胞瘤又称为Wlim’s瘤,是儿童最常见的腹部恶性实体瘤之一,占15岁以下小儿泌尿生殖系统肿瘤的80%以上,偶见于成人。肾母细胞瘤预后与多种因素相关,我们对23例肾母细胞瘤临床病理学资料、p53表达及1号染色体杂合性缺失情况综合分析,判断预后影响因素,为改善患者预后提供参考依据。
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2012年第10期2095-2095,共1页
Chinese Journal of Experimental Surgery
基金
新疆维吾尔自治区科技计划资助项目(201233142)
参考文献5
-
1Sredni ST,de Camargo B, Lopes LF,et al.Immunohistochemical detection of p53 pro-tein expression as a prognostic indicator inWilms tumor. Med Pediatr Oncol, 2001 ,37.455-458.
-
2Farzaneh J, Delaram S, Mohammad R, etal. Immunohistochemical detection of p53protein expression as a prognostic factor inWilms tumor. Iran J Kidney Dis,2011,5 :149-153.
-
3蒙育林,叶江枫,何晋,张国成,李玉松.小儿肾母细胞瘤、髓母细胞瘤p53蛋白的表达及意义[J].临床荟萃,2000,15(13):604-605. 被引量:2
-
4Grundy PE,Breslow NE,Li S,et al. Loss ofheterozygosity for chromosomes lp and 16q isan adverse prognostic factor in favorable-his-tology Wilms tumor: a report from the Na-tional Wilms Tumor Study Group. J Clin On-col ,2005 ,23 ;7312-7321.
-
5Grundy PE, Telzerow PE, Breslow N,et al.Loss of heterozygosity for chromosomes 16qand Ip in Wilms tumors predicts an adverseoutcome. Cancer Res, 1994,54:2331 -2333.
二级参考文献7
-
1黄文清.神经肿瘤病理学[M].上海:上海科学技术出版社,1982.322-323.
-
22,Batsakis JG,EI-Naggar AK.p53:Fifteen years after discovery Advanin AnatoPathol,1995,2:71~88
-
33,Govender D,Harilal P,Hadley GP,et al.p53 protein expression in nephroblastomas:apredictor of poor prognosis.Br J Cancer,1998,77(2):314~318
-
44,EL-Bahtimi R,Hazen Martin DJ,Re GG,et al.Immunophenotype,mRNA expression,and genestructure of p53 in Wilms tumors.Mod Pathol,1996,9(3):238~244
-
55,Karamitopoulou E,Perentes E,Diamantis I.p53 protein expression in central nervoussystem tumors:an immunohistochemical study with CMI polyvalent and DO-7 monoclonalantibodies.Acta Neuropathol Berl,1993,85(6):611~616
-
66,Eah PL,Looi LM,Chan LL.Immumohistochemical expression of p53 proteies in Wilmstumour:a possible association with the histological prognostic parameter ofanaplasia.Hitopathology,1996,28:49~54
-
77,Cahoti C,Thorner P,Malkin D,et al.Immunohistochemical detection of p53 in Wilms tumorscorrelates with unfavorable outcome.Am J Pathol,1996,148:1577~1589
-
1张冰,李鹤平.放射性^(125)I粒子在腹部恶性实体瘤治疗中的应用[J].影像诊断与介入放射学,2011,20(4):313-316. 被引量:4
-
2顾建章,吴宣林.30例失去手术切除机会的小儿腹部恶性实体瘤原因分析[J].现代肿瘤医学,1995,3(2):117-117.
-
3吴宣林,张宪生,徐泉,郭新奎,李鹏.儿童腹部恶性实体瘤的误诊原因及对策[J].现代肿瘤医学,2006,14(9):1100-1102.
-
4曾自三.小儿腹部恶性实体瘤术前介入治疗的临床意义[J].广西医学,2005,27(7):1104-1105. 被引量:1
-
5李长春,王珊,章均,郭春宝,代江涛.介入治疗儿童肝脏恶性肿瘤的疗效与副作用临床探讨[J].中华小儿外科杂志,2009,30(10):681-683.
-
6赵勇,杨铁成,何旭革.男性小儿泌尿生殖系统恶性肿瘤19例诊治体会[J].局解手术学杂志,2004,13(3):185-185.
-
7陈东,王延军,陆伟,周芳坚,张蒙,蔡志明,刘卓炜.腹腔镜根治性肾切除治疗幼儿肾母细胞瘤1例报告[J].中华腔镜泌尿外科杂志(电子版),2015,9(5):61-62. 被引量:3
-
8李楠,杨屹.小儿睾丸肿瘤76例临床分析[J].中华实用儿科临床杂志,2015,30(22):1741-1743. 被引量:3
-
9陈燕,黄书满,文建国.儿童膀胱直肠功能障碍诊断治疗进展[J].中华小儿外科杂志,2015,36(6):477-480. 被引量:5