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细胞窖-1的多重调控机制 被引量:1

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摘要 1953年美国科学家George EP等在观察细胞内吞过程时发现了存在于内皮细胞上的质膜瓶形内陷小窝,将其定义为细胞窖(Caveolae)。后证实Caveolae由鞘糖脂(GSL)、胆固醇、鞘磷脂(SPH)以及糖基锚定膜蛋白组成,其大量存在于内皮细胞、肌细胞、脂肪细胞、肺上皮细胞的细胞膜上,通过蛋白质结构分析,
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第10期2099-2100,共2页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金重点资助项目(81172005) 教育部博士点基金资助项目(20110071120096) 上海市自然科学基金资助项目(11ZR1407000) 复旦大学附属肿瘤医院院级资助基金项目(YJ201002)
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  • 1汪根树,陈规划,陆敏强,杨扬,蔡常洁,朱晓峰,胡斌,司文章.缺血预处理对大鼠部分肝脏切除术后肝脏一氧化氮合酶的影响及意义[J].中华实验外科杂志,2006,23(9):1082-1084. 被引量:5
  • 2Morbidelli L, Donnini S,Ziche M. Role of nitric oxide in the modula- tion of angiogenesis. Curr Pharm Des,2003,9:521-530.
  • 3Tahir SA, Park S, Thompson TC. Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells. Cancer Ther,2009,8 : 2286-2296.
  • 4Parton RG. Cell biology. Life without caveolae. Science 2001, 293: 2404-2405
  • 5Anderson RG. The caveolae membrane system. Annu Rev Biochem 1998,67:199-225
  • 6Drab M, Verkade E Elger M, Kasper M, Lohn M, Lauterbach B, Menne J et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 2001,293:2449-2452
  • 7Tang Z, Scherer PE, Okamoto T, Song K, Chu C, Kohtz DS, Nishimoto I et al. Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem 1996, 271: 2255-2261
  • 8Engelman JA, Zhang X, Galbiati F, Lisanti MP. Chromosomal localization,genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2 and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31). FEB S Lett 1998, 429:330-336
  • 9Liu PS, Rudick M, Anderson RG. Multiple function of caveolin-1. J Biol Chem 2002, 277:41295-41298
  • 10Razandi M, Oh P, Pedram A, Schnitzer J, Levin ER. ERs associate with and regulate the production of caveolin: Implications for signaling and cellular actions. Mol Endocrinol 2002, 16: 100-115

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  • 1Couet J, Belanger MM, Roussel E, et al. Cell biology of caveolae and caveolin[ J]. Adv Drug Deliv Rev,2001,49(3 ) :223-235.
  • 2Goetz JG, Lajoie P,Wiseman SM, et al. Caveolin-1 in tumor progres- sion :the good, the bad and the ugly [ J]. Caneer Metastasis Rev ,2008, 27(4) :715-735.
  • 3Park SS, Kim JE, Kim YA,et al. Caveolin-1 is down-regulated and in- versely correlated with HER2 and EGFR expression status in invasive ductal carcinoma of the breast[ J ]. Histopathology ,2005,47 ( 6 ) :625- 630.
  • 4Wieehen K, Diatehenko L,Agoulnik A, et al. Caveolin-1 is down-regu- lated in human ovarian carcinoma and acts as a eandidate tumor sup- pressor gene [ J ]. Am J Patbo1,2001,159 ( 5 ) : 1635-1643.
  • 5Kim DA, Kim KH, Lee RA. Expression of eaveolin-I is correlatecJ with Akt-1 in colorectal cancer tissues [ J ]. Exp Mol Pathol,2006,80 ( 2 ) : 165-170.
  • 6Van den Eynden GG,Van Laere S J, Van der Auwera I, et al. Overex- pression of caveolin-1 and-2 in cell lines and in human samples of in- flammatory breast cancer[ J]. Breast Cancer Res Treat,2006,95 (3) : 219-228.
  • 7张志波,何庆良,石铮,潘润阳,李国平.肝癌上皮-间叶样表型转化与Caveolin-1表达之间的关系[J].中华实验外科杂志,2009,26(8):970-972. 被引量:7
  • 8高雪,关宏伟,蔡欣,李国生,孙志刚,高鹤立,胡冬梅.Caveolin-1在乳腺癌中的表达及其意义[J].中华普通外科杂志,2011,26(11):928-931. 被引量:3

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