摘要
目的观察越鞠升降汤治疗经前期抑郁的临床疗效。方法将75例经前期抑郁患者随机分为两组,治疗组45例,对照组30例,治疗组以越鞠升降汤治疗,对照组以逍遥丸治疗。两组均以3个月经周期为1个疗程。采用汉密尔顿抑郁量表评定抑郁疗效,观察中医症状改善情况,记录不良反应。结果两组抑郁疗效和临床症状疗效比较,差异均具有统计学意义(P<0.05,或P<0.01);治疗组抑郁和临床症状愈显率和总有效率显著高于对照组(P<0.01),治疗后治疗组中医症状总积分显著低于对照组(P<0.05)。两组均无明显不良反应。结论越鞠升降汤治疗经前期抑郁疗效明显,可靠安全。
Objective To observe the clinical efficacy of Yueju Shengjiang Decoction for relieving stagnation in the treatment of premenstrual depression. Methods Seventy-five patients with premenstrual depression were ran-domly divided into treatment group (n=45) and control group (n=30). The treatment group received therapy with Yueju Shengjiang Decoction, while the control group received therapy with Xiaoyao Pills also for treating stagnation. The course of treatment was three menstrual cycles. The therapeutic effects on depression were as- sessed using Hamilton Depression Scale; the improvement in traditional Chinese medicine (TCM) symptoms was observed; adverse events were recorded. Results There were significant differences in therapeutic effects on depres-sion and clinical symptoms between the two groups (P〈0. 05 ,or P〈0.01). The treatment group showed significantly higher cure and marked response rate and overall response rate than the control group in terms of depression and clini-cal symptoms (P〈0. 01). In addition, the treatment group had significantly lower total scores on TCM symptoms than the control group (P〈0. 05). No adverse events were seen in both groups. Conclusion Yueju Shengjiang De-coction has good clinical efficacy and high safety in the treatment of premenstrual depression.
出处
《安徽中医学院学报》
CAS
2012年第5期23-25,共3页
Journal of Anhui Traditional Chinese Medical College
基金
张家口市科学技术研究与发展计划(1012011D-3)
关键词
抑郁症
越鞠升降汤
逍遥丸
depression
Yueju Shengjiang Decoction
Xiaoyao Pill