血小板假性异常的影响因素分析

Analysis on influence factors of false platelet abnormality

目的探讨血细胞分析仪测定血小板的影响因素,排除"假性增高"和""假性降低"情况。方法使用血细胞分析仪在不同条件下对血小板进行测定,同时采用手工计数,并将二者检测结果进行对比分析。结果采血不当、血小板体积异常、小红细胞数量、溶血标本及放置时间等因素均可造成血小板假性异常。结论全自动血细胞分析仪并不能完全代替手工法,对血小板计数与直方图不符的标本应手工计数或重新采血,以确保结果的准确性。

Objective To study the influence factors of platelet counting detected by the hematology analyzer for exclud- ing the false increase and the false decrease. Methods The hematology analyzer was used to detect platelet counting in different conditions and the manual counting method was simultaneously adopted to perform the conparative analysis on their detected re- sults. Results The factors such as improper blood collection, platelet volume abnormality, microcytes count, hemolytic specimens and placing time could cause the false platelet abnormality. Conclusion The automatic hematology analyzer can not completely replace the manual counting method. The specimens with platelet count inconsistent with the histogram should be rechecked by the manual counting methods or blood recollection to ensure the accuracy of the results.