摘要
目的:分析不规则抗体筛查在临床输血中的应用,降低和避免溶血性输血反应的发生。方法:采用DiaMed微柱凝胶免疫技术(IgG卡)对20000例临床住院申请输血患者标本进行不规则抗体筛查,不规则抗体阳性的标本进行抗体鉴定,同时用DiaMedIgG卡进行交叉配血。分析阳性检出者对临床配血的影响。结果:临床住院申请输血患者标本不规则抗体阳性83例,阳性率0.42%。不规则抗体血型系统的鉴定,Rh系统53例,占63.86%;MNSs系统22例,占26.50%;抗-A13例,占3.61%;P系统1例,占1.20%;Lewis系统3例,占3.61%;Kell系统1例,占1.20%。83例不规则抗体阳性标本均用DiaMedIgG卡进行交叉配血,患者均输注了无相应抗原的红细胞。结论:不规则抗体的筛查,对不规则抗体阳性标本鉴定红细胞抗体,能有效降低和避免溶血性输血反应的发生,保证临床输血安全。
Objective:To explore the significance of screening irregular antibodies in clinical transfusion to de crease or avoid hemolytic transfusion reaction. Method: Irregular antibody screening of 20000 samples were detected with Diamed micro column IgG card. Irregular antibody identification of the positive samples was detected and done cross-match with DiaMed micro column IgG card. The specificity and the frequency of occurrence were ana- lyzed and summarize. Result: 83 samples were positive of irregular antibody and positive rate was 0.42 %. Accord- ing to the detection of the blood group system of the irregular antibodies,Rh system was 52 cases, accounting for 62. 6 5% MNSs system 20 cases, accounting for 24.10 %; anti A1 4 cases, accounting for4.82 %; P system 2 cases, accounting for 2.41%; Lewis system 3 cases, accounting for 3.61%; and Kell system 2 cases, accounting for 2.41%. Conclusion: Screening of irregular antibodies in patients could decrease or avoid hemolytic transfusion reac tion, which would help to ensure the safety of transfusion.
出处
《临床血液学杂志(输血与检验)》
CAS
2012年第5期636-637,共2页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
溶血性输血反应
不规则抗体
输血安全
hemolytic transfusion reaction
irregular antibodies
safety of blood transfusion