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放疗联合唑来膦酸防治脊柱转移癌痛及截瘫 被引量:1

Study of Radiotherapy Combined with Zoledronic Acid in the Prevention and Treatment of Spinal Metastatic Cancer Pain and Paraplegia
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摘要 [目的]探讨放疗联合唑来膦酸治疗脊柱转移癌所致疼痛及截瘫的疗效。[方法]56例恶性肿瘤脊柱转移伴疼痛及肢体活动不灵患者,采用6MVX常规分割放疗,同期给唑来膦酸4mg+生理盐水100ml静滴,3~4周重复,至少连续2次。观察疼痛症状及生活质量改善情况的变化。[结果]56例87个放疗部位止痛总有效率94.3%,生活质量明显改善,总有效率94.7%,20例活动受限的患者中,下肢活动能力评价总有效率90.0%。[结论]放疗联合唑来膦酸在防治脊柱转移癌所致疼痛及截瘫方面有显著疗效,值得临床推广。
出处 《肿瘤学杂志》 CAS 2012年第9期715-716,共2页 Journal of Chinese Oncology
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